Elsevier, eBioMedicine, Volume 79, May 2022
Air pollution and risk of chronic obstructed pulmonary disease: The modifying effect of genetic susceptibility and lifestyle
Background: The effect of long-term exposure to air pollution on the development of chronic obstructive pulmonary disease (COPD) is still controversial, and the role of the interactions of air pollution with genetic risk and lifestyle in COPD risk is unclear. Methods: We included 452762 participants derived from the UK Biobank. Annual concentrations of air pollutions, including particle matter (PM2.5, PM10), nitrogen oxides (NOx), and nitrogen dioxide (NO2), were assessed using land-use regression model.
Elsevier, eClinicalMedicine, Volume 46, April 2022
Background: In autoimmune hepatitis (AIH), clinical practice and treatment guidelines frequently diverge as a reflection of disease heterogeneity and challenges in achieving standardised care. We sought to explore the utility of multiparametric (mp) MR in patients with AIH, and the impact of this technology on physicians’ decision making and intended patient management. Methods: 82 AIH patients, recruited from two sites between June and November 2019 as part of an observational cohort study, underwent non-contrast MRI alongside their standard clinical investigations.
Elsevier, Journal of Aging Studies, Volume 60, March 2022
The complex nature of transportation as a key determinant of health in primary and community care restructuring initiatives in rural Canada
It is well recognized that transportation is a barrier to health-care access for rural-dwelling residents, particularly older adults. Health-care restructuring initiatives seldom take into consideration the complexity of transportation, which acts as a barrier to appropriate and timely access to health-care services for older adults in rural communities.
Elsevier, The Lancet Global Health, Volume 10, February 2022
Cost-effectiveness of universal screening for chronic hepatitis B virus infection in China: an economic evaluation
Background: China has the highest prevalence of hepatitis B virus (HBV) infection worldwide. Universal HBV screening might enable China to reach the WHO 2030 target of 90% diagnostics, 80% treatment, and 65% HBV-related death reduction, and eventually elimination of viral hepatitis. We evaluated the cost-effectiveness of implementing universal HBV screening in China and identified optimal screening strategies.
Elsevier, The Lancet Global Health, Volume 10, January 2022
Mapping low-resource contexts to prepare for lung health interventions in four countries (FRESH AIR): a mixed-method study
Background: Effectiveness of health programmes can be undermined when the implementation misaligns with local beliefs and behaviours. To design context-driven implementation strategies, we explored beliefs and behaviours regarding chronic respiratory disease (CRD) in diverse low-resource settings. Methods: This observational mixed-method study was conducted in Africa (Uganda), Asia (Kyrgyzstan and Vietnam) and Europe (rural Greece and a Roma camp). We systematically mapped beliefs and behaviours using the SETTING-tool.
Elsevier, The Lancet Infectious Diseases, Volume 21, December 2021
Elsevier, The Lancet Respiratory Medicine, Volume 9, November 2021
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
Background: The impact of COVID-19 on physical and mental health and employment after hospitalisation with acute disease is not well understood. The aim of this study was to determine the effects of COVID-19-related hospitalisation on health and employment, to identify factors associated with recovery, and to describe recovery phenotypes.
Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study
The Lancet Planetary Health, Volume 5, November 2021
An Article in support of SDGs 12 and 13, assessing the potential benefits of moving to more sustainable diets for greenhouse gas emissions, land use, mortality, and cancer rates.
Elsevier, The Lancet Public Health, Volume 6, November 2021
Deaths involving COVID-19 by self-reported disability status during the first two waves of the COVID-19 pandemic in England: a retrospective, population-based cohort study
Background: People with learning disabilities are at substantially increased risk of COVID-19 mortality, but evidence on risks of COVID-19 mortality for disabled people more generally is limited. We aimed to use population-level data to estimate the association between self-reported disability and death involving COVID-19 during the first two waves of the COVID-19 pandemic in England.
Elsevier, Ageing Research Reviews, Volume 70, September 2021
Can healthy lifestyle reduce disease progression of Alzheimer's during a global pandemic of COVID-19?
The novel coronavirus disease 2019 (COVID-19) has pushed the medical system to its breaking point. While the virus does not discriminate, the elderly and those with comorbidities, including hypertension severe obesity, diabetes mellitus, coronary disease, pneumonia and dementia, are at a greater risk for adverse outcomes due to COVID-19. While many people navigate their new normal, the question of what the long-lasting effects of the pandemic may be, lingers.