Antiretroviral Therapy

Background: A considerable proportion of people who inject drugs are unstably housed. Although unstable housing is associated with HIV and HCV infection among people who inject drugs, its contribution to transmission is unknown. We estimated the global and national proportions of incident HIV and HCV infections among people who inject drugs attributed to housing instability from 2020 to 2029.
This study supports SDGs 3 and 6 by suggesting that current methods of cholera control are insufficient at achieving zero transmission of Vibrio cholerae in Haiti, and that large-scale cholera vaccination campaigns are needed alongside improvements in water and sanitation for long-term cholera elimination.
In 2016, WHO adopted a strategy for the elimination of viral hepatitis by 2030. Africa, and more specifically, sub-Saharan Africa, carries a substantial portion of the global burden of viral hepatitis, especially chronic hepatitis B and hepatitis C virus infections. The task that lies ahead for sub-Saharan Africa to achieve elimination is substantial, but not insurmountable. Major developments in the management of hepatitis C have put elimination within reach, but several difficulties will need to be navigated on the path to elimination.
HIV Rapid Test being administered (Equality Michigan viaWikimedia Commons)
Background Multistage, stepwise HIV testing and treatment procedures can result in lost opportunities to provide timely antiretroviral therapy (ART). Incomplete engagement of patients along the care cascade translates into high preventable mortality. We aimed to identify whether a structural intervention to streamline testing and linkage to HIV health care would improve testing completeness, ART initiation, and viral suppression and reduce mortality. Methods We did a cluster-randomised, controlled trial in 12 hospitals in Guangxi, China.