Background: China has the highest prevalence of hepatitis B virus (HBV) infection worldwide. Universal HBV screening might enable China to reach the WHO 2030 target of 90% diagnostics, 80% treatment, and 65% HBV-related death reduction, and eventually elimination of viral hepatitis. We evaluated the cost-effectiveness of implementing universal HBV screening in China and identified optimal screening strategies.
Background: Long-term exposure to ambient air pollution has been associated with premature mortality, but associations at concentrations lower than current annual limit values are uncertain. We analysed associations between low-level air pollution and mortality within the multicentre study Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE).
Background: Climate change and air pollution are two major societal problems. Their complex interplay calls for an advanced evaluation framework that can support decision making. Previous assessments have looked at the co-benefits of climate policies for air pollution, but few have optimised air pollution benefits. In our study, we lay out a modelling framework that internalises air pollution's economic impacts on human mortality, while considering climate constraints and aerosol feedback.

Current biology : CB, Volume 32, 10 January 2022

The aim of this profile is to highlight the impact of George Washington Carver’s contributions to modern plant science and to celebrate his achievements as a pioneering interdisciplinary researcher. By discussing his work, in light of recent discoveries in legume symbioses and soil nutrition, the goal is to reveal his foresight and relevance, inspire new generations from diverse backgrounds and contribute to the decolonisation of the curriculum in higher education.
Background: Combustion-related nitrogen dioxide (NO2) air pollution is associated with paediatric asthma incidence. We aimed to estimate global surface NO2 concentrations consistent with the Global Burden of Disease study for 1990–2019 at a 1 km resolution, and the concentrations and attributable paediatric asthma incidence trends in 13 189 cities from 2000 to 2019.
An Article in support of SDGs 3 and 13, highlighting widespread climate anxiety and dissatisfaction with government responses to climate change among chidren globally, with government inaction on climate change described as a human rights failure that could have considerable, long-lasting, and incremental negative implications for the mental health of children and young people.
An Article in support of SDGs 3, 12, and 15, investigating the adverse effects of deforestation on working conditions and all-cause mortality, highlighting how conservation and restoration projects could help to achieve public health benefits.
Plant-based meat analogs are likely to have different gastrointestinal fates than real meat products due to differences in their compositions and structures. Here, we compared the gastrointestinal fate of ground beef and ground beef analogs using the INFOGEST in vitro digestion model, focusing on differences in microstructure, physicochemical properties, lipid digestion, and protein digestion in different regions of the model gut.
Introduction: Women continue to be underrepresented in oncology clinical trials, leading to poor, underpowered subgroup analyses that cannot be generalized to cancer patients in practice. In 2014, the US Food and Drug Administration (FDA) released an Action Plan, which included actions to improve the quality and reporting of demographic subgroup data. We sought to evaluate the five-year progress since the release of this report by assessing the credibility of sex-specific subgroup analyses in oncology clinical trials.
Elsevier, The Lancet Infectious Diseases, Volume 21, December 2021