Elsevier,
Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology, Volume 271, September 2023
OKA is a potent neurotoxin and has a profound effect on cognitive dysfunction in Zebrafish. 4D and 10D OKA treated zebrafish show significant changes in gene expressions related to neuroinflammation. OKA exposed zebrafish display a substantial number of proteins that are involved in contributing to AD pathology. OKA-induced AD in zebrafish model can be used as a screening tool to explore further underlying possible mechanisms.
Elsevier, The Lancet Healthy Longevity, Volume 4, August 2023
The demand for health care in older people involved in the criminal justice system is high. The prevalence of mental and physical health conditions for people living in prison is greater than in community populations. After systematically searching 21 databases, we found no targeted interventions to support depression or anxiety for this group of people.
Elsevier,
The Lancet Regional Health - Southeast Asia, Available online 24 August 2023, 100257
This Article supports Sustainable Development Goal 3 by estimating the prevalence of dementia in people aged 60 years and older in Bangladesh, finding an overall prevalence of 8%, and identifying positive associations between dementia prevalence and female sex, advanced age, and lower education levels.
Elsevier,
Theriogenology Wild, Volume 3, 2023, 100050
Humpback whales (Megaptera novaeangliae) in Southeast Alaska have been studied for over 50 years, and are largely considered a recovery success since the cessation of commercial whaling. To further sustain this success we need to improve our knowledge of how these giants reproduce. The authors developed an effective strategy for monitoring the hormone levels in a challenging natural environment.
Elsevier,
eBioMedicine, Volume 94, August 2023
This Article supports Sustainable Development Goal 3 by identifying an independent relationship between anxiety and subsequent cognitive progression in older people without dementia; these findings suggest that treating anxiety and targeting mitochondrial dysfunction may be effective in preventing dementia.
Elsevier,
eBioMedicine, Volume 94, August 2023
This Article supports Sustainable Development Goal 3 by advancing our understanding of the possible role of active immunotherapy against amyloid-β in individuals with mild Alzheimer's disease; the findings of this phase 2a study support the continued clinical development of UB-311 as an active immunotherapy for Alzheimer's disease.
Elsevier,
The Lancet Healthy Longevity, Volume 4, August 2023
This Article supports Sustainable Development Goal 3 by showing that although there was an increase in prescribing of antipsychotics to people with dementia during the COVID-19 pandemic, this increase was not responsible for the large increase in all-cause and stroke mortality in this population.
