Articles

Main participants in a PPP—core strengths and key benefits in drug discovery/development. The figure provides an overview of the main participants in a PPP, highlights their core strengths, and lists important benefits across the various stages of the dru
Elsevier,

SLAS Discovery, Volume 26, June 2021

Collaborative efforts between public and private entities such as academic institutions, governments, and pharmaceutical companies form an integral part of scientific research, and notable instances of such initiatives have been created within the life science community. Several examples of alliances exist with the broad goal of collaborating toward scientific advancement and improved public welfare. Such collaborations can be essential in catalyzing breaking areas of science within high-risk or global public health strategies that may have otherwise not progressed. A common term used to describe these alliances is public-private partnership (PPP). This review discusses different aspects of such partnerships in drug discovery/development and provides example applications as well as successful case studies. Specific areas that are covered include PPPs for sharing compounds at various phases of the drug discovery process—from compound collections for hit identification to sharing clinical candidates. Instances of PPPs to support better data integration and build better machine learning models are also discussed. The review also provides examples of PPPs that address the gap in knowledge or resources among involved parties and advance drug discovery, especially in disease areas with unfulfilled and/or social needs, like neurological disorders, cancer, and neglected and rare diseases.
Elsevier, Journal of Pediatric Nursing, Volume 58, 1 May 2021
Problem: Today, one in four children in the world lives in an area of conflict or disaster, and more than 30 million have been displaced, enslaved or trafficked, abused, and exploited. However, there is little recognition of nursing interventions in this context and their impact on the quality of life. Eligibility Criteria: Studies that (1) Described nursing interventions in children under situations of armed conflict. (2) Identified the impact of the interventions in the Quality of Life. (3) identify research trends in the field by nursing professionals.
Elsevier, Transportation Research Part E: Logistics and Transportation Review, Volume 149, May 2021
In this paper, we address the problem of humanitarian aids distribution across refugee camps in war-ridden areas from a network design perspective. We show that the problem can be modeled as a variant of multi-period hub location problem with a particular demand pattern resulted by the user's behavior. The problem has been motivated by a case study of Lebanese experience in Syrian war refugee accommodation. We elaborate on the complexity and real-life constraints and, propose a compact formulation of a mathematical model of the problem.
Elsevier, One Earth, Volume 4, 21 May 2021
Globally, financial services are well positioned to contribute to the transformation needed for sustainable futures and will be critical for supporting corporate activities that regenerate and promote biosphere resilience as a key strategy to confront the new risk landscape of the Anthropocene. While current financial risk frameworks focus primarily on financial materiality and risks to the financial sector, failure to account for investment externalities will aggravate climate and other environmental change and set current sustainable finance initiatives off course.
Elsevier,

Heliyon, Volume 7, May 2021

After a massive disaster, many residents in affected areas are forced to temporarily stay in evacuation shelters. The exact impact of the state of resource supply and infrastructure in evacuation shelters on the health status of evacuees has not been sufficiently studied. Two weeks after the 2011 Great East Japan Earthquake (GEJE), comprehensive surveillance related to the health status and hygiene level was performed for all evacuation shelters (328 shelters with 46,480 evacuees at the peak) in one of the most devastating medical zones after the tsunami hit the area (Ishinomaki City).

Elsevier,

Telematics and Informatics, Volume 58, May 2021

We investigate the role of creative skilled migrants in broadcasting an alternative use of technology in support of a sustainable smart city. We do so by analyzing the themes they produced on Twitter. We focus on Amsterdam as a case, and urban planners and designers as examples of creative migrants. Computational methodology allowed for a selection of naturally occurring data in social media.

Elsevier,

EClinicalMedicine, Volume 35, May 2021

This Article supports SDGs 3 and 10 by showing how a remote prenatal education package aimed at First Nations pregnant women in Manitoba, Canada, was able to increase prenatal programme participation and breastfeeding initiation in this community. The study shows that such a programme is feasible and effective and can be a useful supplement to existing prenatal programmes in such communities.
Elsevier, AJOG Global Reports, Volume 1, May 2021
Newly married women in Nepal experience increasing levels of violence over time. Intimate partner violence was positively associated with recent pregnancy and childbirth.
Elsevier,

Marine Micropaleontology, Volume 165, May 2021

Ostracod assemblages near the boundary between land and sea have been affected by multiple complex factors, such as regional climate and depositional and human-induced processes during the Late Holocene.
Elsevier,

The Lancet, Volume 397, 8 May 2021

This Article supports SDGs 3 and 10 by showing that some minority ethnic populations in England have excess risks of testing positive for SARS-CoV-2 and of adverse COVID-19 outcomes compared with the White population, even after accounting for differences in sociodemographic, clinical, and household characteristics.

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