Cold Regions Science and Technology, Volume 189, September 2021
Inventory of infrastructure potentially built on permafrost in the French Alps. Evaluation and ranking of the most at-risk infrastructures built on permafrost. Adaption and mitigation strategies already used to prevent or to cope with the destabilization.
Elsevier,
Applications in Energy and Combustion Science, Volume 7, September 2021
This opinion article is the result of intensive discussions between a group of more than fifty internationally renowned researchers who are scientifically engaged in thermofluids and energy process engineering. With this article we express our plea: Let us consider all options and explore new ideas that will move us towards a climate-neutral energy system!
Elsevier,
The Journal of Climate Change and Health, Volume 4, 2021, 100058
This paper presents an initial qualitative exploration of United States physicians’ perspectives with regard to whether, why and how physicians might discuss the health effects of global environmental change, climate change in particular, with their patients and what would need to change in healthcare systems to facilitate this.
The novel coronavirus disease 2019 (COVID-19) has pushed the medical system to its breaking point. While the virus does not discriminate, the elderly and those with comorbidities, including hypertension severe obesity, diabetes mellitus, coronary disease, pneumonia and dementia, are at a greater risk for adverse outcomes due to COVID-19. While many people navigate their new normal, the question of what the long-lasting effects of the pandemic may be, lingers.
Elsevier, Behavioural Brain Research, Volume 414, 24 September 2021
Rho-associated coiled-coil kinase (ROCK), a serine/threonine kinase regulated by the small GTPase RhoA, is involved in regulating cell migration, proliferation, and survival. Numerous studies have shown that the RhoA/ROCK signaling pathway can promote Alzheimer's disease (AD) occurrence. ROCK activation increases β-secretase activity and promotes amyloid-beta (Aβ) production; moreover, Aβ further activates ROCK. This is suggestive of a possible positive feedback role for Aβ and ROCK. Moreover, ROCK activation promotes the formation of neurofibrillary tangles and abnormal synaptic contraction.
