Elsevier, Clinical Imaging, Volume 90, October 2022
Several studies of adult-onset multiple sclerosis (AOMS) patients have demonstrated that spinal cord volume loss is associated with disease progression and clinical disability; however, complementary studies of young patients with pediatric-onset multiple sclerosis (POMS) are lacking. In the context of SDG Goal 3, this retrospective study aimed to assess spinal cord volume in POMS patients compared with that in healthy controls.
Elsevier, Preventive Medicine Reports, Volume 29, October 2022
People with any disabilities accounted for a quarter of total deaths. People with disabilities had higher average ages and poor economic conditions. All disability types presented higher mortality rates and lower life expectancy. The major causes of death differed according to the type of disability.
eClinicalMedicine, Volume 52, October 2022
This Article supports SDG 3 and 5 by highlighting a need for greater involvement of in-country authors on research examining a wider range of gendered COVID-19 impacts, as well as increased representation of diverse topics and publications related to COVID-19 and women's well-being focused on lower income countries.
Redox Biology, Volume 56, October 2022
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disorder characterized by progressive muscle weakness. Adenine nucleotide translocator 1 (ANT1), the only 4q35 gene involved in mitochondrial function, is strongly expressed in FSHD skeletal muscle biopsies. However, its role in FSHD is unclear. In this study, we evaluated ANT1 overexpression effects in primary myoblasts from healthy controls and during Xenopus laevis organogenesis. We also compared ANT1 overexpression effects with the phenotype of FSHD muscle cells and biopsies.
Redox biology, Volume 56, 1 October 2022
Deficits in mitochondrial function and redox deregulation have been attributed to Huntington's disease (HD). However, whether these changes occur in early stages of the disease and can be detected in vivo is still unclear. In this article, the authors analysed changes in mitochondrial function and production of reactive oxygen species (ROS) at early stages and with disease progression.
The Lancet Oncology, Volume 23, September 2022
This Article supports SDG 3 by estimating the impacts of the centralisation of specialist cancer services, focusing on travel time, equity of access, outcomes, and hospital workload. Using rectal cancer surgery centres as an example the authors found increases in travel times but reductions in readmission rates.
Elsevier, The Lancet Public Health, Volume 7, September 2022
This Article supports SDGs 5, 8, and 10 by investigating the prevalence of workplace sexual harassment and violence by demographic factors and work sectors among Icelandic women, providing nuanced targets for prevention and for public policies aimed at promoting women’s safety in the work environment.