Cell Engineering

Graphical abstract showing the effect of estrogen-deficiency on a tooth
Emerging evidence indicates that postmenopausal women with periodontitis have aggravated inflammation and prolonged course, with the detailed mechanisms largely unknown. This study aimed to determine the pathogenic role of aberrant extracellular vesicles due to imbalanced-polarized macrophages and explore the therapeutic approach for periodontitis in postmenopausal individuals. Periodontitis in ovariectomized (OVX) mouse models were established to simulate the aggravated periodontitis in postmenopausal women.
Repair of injured skeletal muscle is a sophisticated process that uses immune, muscle, perivascular, and neural cells. In acute injury, the robust endogenous repair process can facilitate complete regeneration with little to no functional deficit. However, in severe injury, the damage is beyond the capacity for self-repair, often resulting in structural and functional deficits. Aside from the insufficiencies in muscle function, the aesthetic deficits can impact quality of life.
Elsevier, Trends in Food Science and Technology, Volume 97, March 2020
Background: Cultured meat has emerged as a breakthrough technology for the global food industry, which was considered as a potential solution to mitigate serious environmental, sustainability, global public health, and animal welfare concerns in the near future. Although there is promise that cultured meat can supplement or even replace conventional meat, many challenges still need to be resolved in the early stages.
Elsevier, Renewable and Sustainable Energy Reviews, Volume 68, 1 February 2017
Trees, and their derivative products, have been used by societies around the world for thousands of years. Contemporary construction of tall buildings from timber, in whole or in part, suggests a growing interest in the potential for building with wood at a scale not previously attainable. As wood is the only significant building material that is grown, we have a natural inclination that building in wood is good for the environment. But under what conditions is this really the case?