This study supports SDGs 3 and 6 by showing that a handwashing intervention involving disgust-inducing messages, combined with the provision of handwashing stations in Abidjan, Côte d'Ivoire, successfully increased rates of handwashing with soap after toilet use. These findings demonstrate the effectiveness of combining health-based messaging with non-health-based messaging when implementing water, sanitation, and hygiene interventions.
, Ageing Research Reviews, Volume 70, September 2021
The novel coronavirus disease 2019 (COVID-19) has pushed the medical system to its breaking point. While the virus does not discriminate, the elderly and those with comorbidities, including hypertension severe obesity, diabetes mellitus, coronary disease, pneumonia and dementia, are at a greater risk for adverse outcomes due to COVID-19. While many people navigate their new normal, the question of what the long-lasting effects of the pandemic may be, lingers.
, Neurochemistry International, Volume 147, July 2021
Alzheimer's disease (AD) is by far the most prevalent neurodegenerative disease of aging and is a major burden for patients, caregivers, and the overall health care system. The complexity of AD pathophysiology and the lack of deep understanding of disease mechanisms impeded the development of AD therapy. Currently approved treatments for AD only modestly improve cognitive function but do not modify disease course. The lack of pharmacological approaches has led to the consideration of alternative strategies to prevent or to slow down the progression of AD.
, Clinical Simulation in Nursing, Volume 55, June 2021
Background: Simulation-based experiences provide learning opportunities into the world of people living with dementia, however limited research into its effectiveness exists. Methods: A quasi-experimental design was used to examine the impact of the virtual dementia tour on empathetic thinking, understanding and person care. Study participants included carers and multi-health professionals (n = 223). Results: Empathetic understanding of symptoms, its impact on the provision of person-centred practice were all scored as neutral.
, Public Health, Volume 194, May 2021
Objectives: In the face of the SARS-CoV-2 pandemic, people with dementia and their carers are contending with serious challenges to their health and wellbeing, due to risk of severe illness, limiting of social contact and disruption to usual activities. Many forms of support for people with dementia and their carers, including singing groups, have moved online using videoconferencing. Previous research has demonstrated the benefits of group singing, which include cognitive stimulation, meaningful activity and peer support.
, Progress in Retinal and Eye Research, Volume 82, May 2021
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically characterised by cognitive deficits that gradually worsen over time. There is, at present, no established cure, or disease-modifying treatments for AD. As life expectancy increases globally, the number of individuals suffering from the disease is projected to increase substantially. Cumulative evidence indicates that AD neuropathological process is initiated several years, if not decades, before clinical signs are evident in patients, and diagnosis made.
, EBioMedicine, Volume 67, May 2021
Background: The pathological changes in Alzheimer's Disease (AD) and other neurodegenerative disorders begin decades prior to their clinical expression. However, the clinical diagnosis of neurodegenerative dementias is not straightforward. Lactoferrin is an iron-binding, antimicrobial glycoprotein with a plethora of functions, including acting as an important immune modulator and by having a bacteriocidic effect. Two previous studies indicated that salivary lactoferrin could differentiate between neurodegenerative dementias.
, The Lancet Public Health, Volume 6, March 2021
Background: The population of older adults (ie, those aged ≥55 years) in England is becoming increasingly ethnically diverse. Previous reports indicate that ethnic inequalities in health exist among older adults, but information is limited by the paucity of data from small minority ethnic groups. This study aimed to analyse inequalities in health-related quality of life (HRQoL) and five determinants of health in older adults across all ethnic groups in England.
, Journal of the American Academy of Dermatology, Volume 84, March 2021
The Lancet Public Health, Volume 6, March 2021
This Article supports SDGs 3 and 10 by evaluating ethnic inequalities in health among older adults (55 years or older) in England. The large, cross-sectional study includes more than a million survey respondents, and identifies wide ethnic inequalities in health-related quality of life, prevalence of long-term conditions, experiences of primary care, support from local services, and confidence in managing one's own health. Outcomes varied widely between minority ethnic groups, both in the direction and magnitude of associations.