, Journal of Hazardous Materials Letters, Volume 2, November 2021
Vinyl chloride (VC) and 1,4-dioxane (DX) are carcinogens and co-occurring groundwater pollutants. Co-contaminants often affect the ability of microorganisms to biodegrade individual constituents. One of the mechanisms by which microbial cells overcome toxic inhibition is by transforming the inhibitory compounds. In this study, while VC inhibited DX biodegradation, it was surprisingly utilized as a growth substrate by Pseudonocardia dioxanivorans CB1190. Increasing concentrations of VC decreased DX biodegradation rates, whereas increasing DX did not have a strong effect on VC biodegradation.