Elsevier, Behavioural Brain Research, Volume 414, 24 September 2021
Rho-associated coiled-coil kinase (ROCK), a serine/threonine kinase regulated by the small GTPase RhoA, is involved in regulating cell migration, proliferation, and survival. Numerous studies have shown that the RhoA/ROCK signaling pathway can promote Alzheimer's disease (AD) occurrence. ROCK activation increases β-secretase activity and promotes amyloid-beta (Aβ) production; moreover, Aβ further activates ROCK. This is suggestive of a possible positive feedback role for Aβ and ROCK. Moreover, ROCK activation promotes the formation of neurofibrillary tangles and abnormal synaptic contraction.
Elsevier, Agriculture, Ecosystems and Environment, Volume 304, 1 December 2020
Pasture in crop rotations influences microbial biodiversity and function reducing the potential for nitrogen loss from compost
Agroecosystems make up a significant portion of terrestrial ecosystems and receive a disproportionally high amount of terrestrial nitrogen inputs from fertilizer, leading to nitrogen loss and associated environmental problems. Integrated crop livestock systems, such as pasture-integrated crop rotations, may be more environmentally sustainable however the long-term effects of this management practice on soil microorganisms and nitrogen transformations are not well understood.
Elsevier, Soil Biology and Biochemistry, Volume 149, October 2020
Fire is an ecological disturbance that alters soil microbiomes and the functions they mediate in terrestrial ecosystems. Soil microbial diversity in Mediterranean Basin ecosystems shows resilience to fire following the restoration of plant-soil feedbacks. We hypothesised that microbial functions related to organic matter decomposition and nutrient cycling might show similar patterns of recovery.
Elsevier, Agricultural Water Management, Volume 235, 31 May 2020
Heavy metal accumulation and changes in soil enzymes activities and bacterial functional diversity under long-term treated wastewater irrigation in East Central region of Tunisia (Monastir governorate)
Climate change and population growth generates a decrease in water availability around the world which can compromise the maintenance of sustainable agriculture. Thus, treated wastewater (TWW) became an alternative to minimize water shortage. However, this may indirectly affect the soil's microbial properties. In this study different soils irrigated for 0, 1, 8 and 20 years with TWW were sampled and from the east central region of Tunisia.
Elsevier, TrAC - Trends in Analytical Chemistry, Volume 111, February 2019
Ecotoxicological effects of microplastics: Examination of biomarkers, current state and future perspectives
Interest about interactions between microplastics and organisms is on the rise. Accessing organisms’ responses to these chemically “inert” compounds plays an important role in determining their potential toxicity. Microplastics from the environment tend to accumulate and move through living organisms, inducing a variety of biological effects, such as disturbances in energy metabolism, oxidative balance, antioxidative capacity, DNA, immunological, neurological and histological damage.
Elsevier, Pedobiologia, Volume 69, July 2018
When biochar (BC) ages in soil, its properties change substantially: cation exchange capacity (CEC), surface area and porosity increase and water repellency decreases, consequently affecting the interactions with soil microorganisms. Activation of BC by organic acids may be regarded as artificial aging. Here, we study the effect of acid-activated BCs on soil microbial enzyme activities (EA) in comparison to several different control treatments without activated BC. A greenhouse pot experiment was conducted using a vineyard soil treated with multiple soil additives (four replications).
Elsevier, Pedobiologia, Volume 66, January 2018
Assessment of soil microbial functional diversity: land use and soil properties affect CLPP-MicroResp and enzymes responses
The assessment of microbial functional diversity is an important indicator of soil quality. Different methodological approaches are currently used; among them are enzyme activities (EA) and CLPP (community level physiological profile) techniques (e.g. MicroResp™ MR).