Study objective: This scoping review was conducted to collate and summarize the published research literature addressing sexual and gender minority care in the emergency department (ED). Methods: Using PRISMA-ScR criteria, an electronic search was conducted of CINAHL, Embase, Ovid Medline, and Web of Science for all studies that were published after 1995 involving sexual and gender minorities, throughout all life stages, presenting to an ED. We excluded non-US and Canadian studies and editorials.
Background: Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen–drug combinations in select locations. To our knowledge, this study presents the most comprehensive estimates of AMR burden to date. Methods: We estimated deaths and disability-adjusted life-years (DALYs) attributable to and associated with bacterial AMR for 23 pathogens and 88 pathogen–drug combinations in 204 countries and territories in 2019.
Background & aims: Recent experimental models and epidemiological studies suggest that specific environmental contaminants (ECs) contribute to the initiation and pathology of non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanisms linking EC exposure with NAFLD remain poorly understood and there is no data on their impact on the human liver metabolome. Herein, we hypothesized that exposure to ECs, particularly perfluorinated alkyl substances (PFAS), impacts liver metabolism, specifically bile acid metabolism.
Figure illustrating the intervention delivery and data collection timeline.
This study supports SDGs 3 and 6 by investigating a low-cost behavioural intervention designed to increase latrine use and safe disposal of child faeces in India. The study found the intervention modestly increased latrine use and markedly increased safe disposal of child faeces in the short term, but was unlikely to reduce exposure to pathogens to a level necessary to achieve health gains.
The COVID-19 pandemic is unprecedented. The pandemic not only induced a public health crisis, but has led to severe economic, social, and educational crises. Across economies and societies, the distributional consequences of the pandemic have been uneven. Among groups living in vulnerable conditions, the pandemic substantially magnified the inequality gaps, with possible negative implications for these individuals' long-term physical, socioeconomic, and mental wellbeing.
This Personal View supports SDGs 3 and 6 by suggesting a scale-specific approach in which agricultural water use is embedded in a larger systems approach to allow the design of effective incentives to change and optimise agricultural water use.
Elsevier, Current Opinion in Chemical Biology, Volume 65, December 2021
Drug repurposing aims to find new uses for already existing and approved drugs. We now provide a brief overview of recent developments in drug repurposing using machine learning alongside other computational approaches for comparison. We also highlight several applications for cancer using kinase inhibitors, Alzheimer's disease as well as COVID-19.
Elsevier, Current Opinion in Behavioral Sciences, Volume 42, December 2021
How can we as individuals or groups mitigate climate change? One key issue is whether motives other than the pursuit of material self-interest can be used fruitfully to reduce climate change. In this article I describe recent research that supports three deeply rooted concerns: (a) concern with other humans (prosociality), (b) concern with equality (egalitarianism), and (c) concern with animals (as part of adherence to biospheric values).
Elsevier, The Lancet Infectious Diseases, Volume 21, December 2021