Elsevier, Digestive and Liver Disease, Volume 54, June 2022
Clinical update on risks and efficacy of anti-SARS-CoV-2 vaccines in patients with autoimmune hepatitis and summary of reports on post-vaccination liver injury
Patients with liver diseases, especially those with cirrhosis, have an increased mortality risk when infected by SARS-CoV-2 and therefore anti-SARS-CoV-2 vaccine has been recommended by leading Scientific Associations for all patients with chronic liver diseases. However, previous reports have shown a reduced antibody response following the full course of vaccination in immunosuppressed patients, including liver transplant recipients and several rheumatic diseases.
Elsevier, The Lancet Planetary Health, Volume 6, March 2022
Associations between ambient temperature and enteric infections by pathogen: a systematic review and meta-analysis
Background: Numerous studies have quantified the associations between ambient temperature and enteric infections, particularly all-cause enteric infections. However, the temperature sensitivity of enteric infections might be pathogen dependent. Here, we sought to identify pathogen-specific associations between ambient temperature and enteric infections.
Elsevier, Annals of Emergency Medicine, Volume 79, February 2022
Study objective: This scoping review was conducted to collate and summarize the published research literature addressing sexual and gender minority care in the emergency department (ED). Methods: Using PRISMA-ScR criteria, an electronic search was conducted of CINAHL, Embase, Ovid Medline, and Web of Science for all studies that were published after 1995 involving sexual and gender minorities, throughout all life stages, presenting to an ED. We excluded non-US and Canadian studies and editorials.
Elsevier, The Lancet, Volume 399, 12 February 2022
Background: Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen–drug combinations in select locations. To our knowledge, this study presents the most comprehensive estimates of AMR burden to date. Methods: We estimated deaths and disability-adjusted life-years (DALYs) attributable to and associated with bacterial AMR for 23 pathogens and 88 pathogen–drug combinations in 204 countries and territories in 2019.
Elsevier, Journal of Hepatology, Volume 76, February 2022
Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease
Background & aims: Recent experimental models and epidemiological studies suggest that specific environmental contaminants (ECs) contribute to the initiation and pathology of non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanisms linking EC exposure with NAFLD remain poorly understood and there is no data on their impact on the human liver metabolome. Herein, we hypothesized that exposure to ECs, particularly perfluorinated alkyl substances (PFAS), impacts liver metabolism, specifically bile acid metabolism.
Elevated levels of antibiotic resistance in groundwater during treated wastewater irrigation associated with infiltration and accumulation of antibiotic residues
Journal of Hazardous Materials, Volume 423, 5 February 2022
Effect of a low-cost, behaviour-change intervention on latrine use and safe disposal of child faeces in rural Odisha, India: a cluster-randomised controlled trial
The Lancet Planetary Health, Volume 6, February 2022
This study supports SDGs 3 and 6 by investigating a low-cost behavioural intervention designed to increase latrine use and safe disposal of child faeces in India. The study found the intervention modestly increased latrine use and markedly increased safe disposal of child faeces in the short term, but was unlikely to reduce exposure to pathogens to a level necessary to achieve health gains.
Elsevier, The Lancet Public Health, Volume 7, February 2022
The contribution of unstable housing to HIV and hepatitis C virus transmission among people who inject drugs globally, regionally, and at country level: a modelling study
Background: A considerable proportion of people who inject drugs are unstably housed. Although unstable housing is associated with HIV and HCV infection among people who inject drugs, its contribution to transmission is unknown. We estimated the global and national proportions of incident HIV and HCV infections among people who inject drugs attributed to housing instability from 2020 to 2029.
Optimising the water we eat—rethinking policy to enhance productive and sustainable use of water in agri-food systems across scales
The Lancet Planetary Health, Volume 6, January 2022
This Personal View supports SDGs 3 and 6 by suggesting a scale-specific approach in which agricultural water use is embedded in a larger systems approach to allow the design of effective incentives to change and optimise agricultural water use.
Elsevier, The Lancet Public Health, Volume 7, January 2022
Safeguarding people living in vulnerable conditions in the COVID-19 era through universal health coverage and social protection
The COVID-19 pandemic is unprecedented. The pandemic not only induced a public health crisis, but has led to severe economic, social, and educational crises. Across economies and societies, the distributional consequences of the pandemic have been uneven. Among groups living in vulnerable conditions, the pandemic substantially magnified the inequality gaps, with possible negative implications for these individuals' long-term physical, socioeconomic, and mental wellbeing.