Elevated levels of antibiotic resistance in groundwater during treated wastewater irrigation associated with infiltration and accumulation of antibiotic residues
Journal of Hazardous Materials, Volume 423, 5 February 2022
Elsevier, Journal of Virological Methods, Volume 291, May 2021
Rapid and sensitive detection of hepatitis B virus by lateral flow recombinase polymerase amplification assay
Hepatitis B virus (HBV) infection is a major public health priority. In the present study, a lateral flow strip combined with the recombinase polymerase amplification (LF-RPA) assay was developed and evaluated for rapid HBV detection. A primer/probe pair targeting the conserved region of the HBV genome was designed and applied to the LF-RPA. TheRPA was achieved at the isothermal temperature of 39℃ for 30 min, and the RPA products were detected using the LF test. DNA extraction, RPA reaction and endpoint detection will take about 70 min.
Elsevier, Behavioural Brain Research, Volume 402, 26 March 2021
Effects of melatonin and resveratrol on recognition memory and passive avoidance performance in a mouse model of Alzheimer's disease
Alzheimer's disease (AD) is the foremost cause of dementia among other neurodegenerative diseases, leading to memory loss and cognitive deficits. AD has gained extensive attention in research for exploring possible interventions. One promising field is natural substances and compounds that could provide a wide range of neuroprotection against AD. This study aimed to investigate the possible effects of melatonin (MEL) and resveratrol (RES) in improving memory deficits in a sporadic mouse model of AD. Memory deficit was induced using AlCl3 and d-galactose for generating an AD mouse model.
Elsevier, JAAD Case Reports, Volume 6, December 2020
Elsevier, EBioMedicine, Volume 59, September 2020
Gut mycobiome and its interaction with diet, gut bacteria and alzheimer's disease markers in subjects with mild cognitive impairment: A pilot study
Background: Recently, we reported that patients with mild cognitive impairment (MCI) harbor specific signature of bacteria in their gut and that a modified Mediterranean ketogenic diet (MMKD) improves Alzheimer's disease (AD) markers in cerebrospinal fluid (CSF) and the signatures of gut bacteria. However, other microbial population such as gut fungi (mycobiome) in relation to MCI/AD pathology, gut bacteria and diet remain unknown.
Elsevier, Journal of Molecular Diagnostics, Volume 22, July 2020
Elsevier, Soil and Tillage Research, Volume 198, April 2020
Nitrogen transformation processes and gaseous emissions from a humic gley soil at two water filled pore spaces
The artificial drainage of heavy textured gley soils is prevalent on pasture. Drainage of a soil profile reduces the water filled pore space (WFPS) in the upper soil horizons with consequences for N2 and N2O emissions, the fate of nitrogen (N), transformational processes and microbial and bacterial communities. The present intact soil column study with isotopically enriched fertiliser investigates all these aspects simultaneously under two WFPS treatments (80% (HS) and 55% (LS) saturation).
Elsevier, The Lancet Gastroenterology and Hepatology, Volume 2, October 2017
Primary antibiotic resistance in Helicobacter pylori in the Asia-Pacific region: a systematic review and meta-analysis
Background So far, a comprehensive systematic review and meta-analysis has not been done of the prevalence of primary antibiotic resistance in Helicobacter pylori in the Asia-Pacific region. We aimed to assess the trends and regional differences in primary antibiotic resistance to H pylori in the Asia-Pacific region and to examine the relation between resistance and first-line eradication. Methods We did a systematic review and meta-analysis of primary antibiotic resistance to H pylori and the efficacy of first-line regimens in the Asia-Pacific region.
Elsevier, The Lancet HIV, Volume 4, September 2017
Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study
Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour. Methods We invited men and transgender women who have sex with men, previously enrolled in the randomised placebo-controlled ANRS IPERGAY trial at seven sites (six in France and one in Canada), to participate in an open-label extension with on-demand tenofovir disoproxil fumarate (300 mg) and emtricitabine (200 mg) to be taken before and after sexual intercourse.