Elsevier, EClinicalMedicine, Volume 32, February 2021
Sleep disruption and Alzheimer's disease risk: Inferences from men with benign prostatic hyperplasia: Benign prostatic hyperplasia and dementia
Background: Sleep disturbances may increase risks of Alzheimer's disease (AD) and other dementias. Benign prostatic hyperplasia (BPH) is usually associated with lower urinary tract symptoms, including nocturia, and thereby disturbed sleep. We examined if men with BPH are at increased risk of AD and all-cause dementia. Methods: In a Danish nationwide cohort (1996–2016), we identified 297,026 men with BPH, defined by inpatient or outpatient hospital diagnosis or by BPH-related surgical or medical treatment, and 1,107,176 men from the general population matched by birth year.
This study supports SDG 3 and 10 by reporting that Māori and Pacific people with type 2 diabetes have consistently poorer health outcomes than European patients, indicating the need for specific policies and interventions to better manage type 2 diabetes in these subpopulations.
Study objective: We examine racial and ethnic differences in opioid prescribing and dosing for long bone fractures at emergency department (ED) discharge. Methods: We conducted an electronic health records–based cross-sectional study of adults with long bone fractures who presented to the ED across 22 sites from a health care delivery system (2016 to 2017).
Elsevier, The Lancet Infectious Diseases, Volume 17, 1 February 2017
A global call from five countries to collaborate in antibiotic stewardship: united we succeed, divided we might fail
In February, 2016, WHO released a report for the development of national action plans to address the threat of antibiotic resistance, the catastrophic consequences of inaction, and the need for antibiotic stewardship. Antibiotic stewardship combined with infection prevention comprises a collaborative, multidisciplinary approach to optimise use of antibiotics. Efforts to mitigate overuse will be unsustainable without learning and coordinating activities globally.