, Trends in Ecology and Evolution, Volume 33, December 2018
Rapid ocean warming as a result of climate change poses a key risk for coral reefs. Even if the goals of the Paris Climate Agreement are achieved, coral reefs are likely to decline by 70–90% relative to their current abundance by midcentury. Although alarming, coral communities that survive will play a key role in the regeneration of reefs by mid-to-late century.
, Marine Pollution Bulletin, Volume 136, November 2018
Increasing accessibility of coral reefs from the latter third of the 20th century led quickly to recognition of the vulnerability of coral reef communities to a combination of direct and indirect human impacts. Coral reefs are confronted by the stark threats of climate and ocean changes from the increasing number, intensity and forms of human use impacting global and marine systems. Management, particularly of accessible coral reefs, occurs in the context of multiple scale transboundary water column linkages of lifecycle processes and increasing human use of coastal and marine space.
, Neuron, Volume 100, 24 October 2018
Recent progress in the genomics of non-syndromic autism spectrum disorder (nsASD) highlights rare, large-effect, germline, heterozygous de novo coding mutations. This distinguishes nsASD from later-onset psychiatric disorders where gene discovery efforts have predominantly yielded common alleles of small effect. These differences point to distinctive opportunities for clarifying the neurobiology of nsASD and developing novel treatments.
, Trends in Ecology and Evolution, Volume 33, August 2018
Efforts to protect nature are facing a growing crisis, one that often revolves around the burgeoning impacts of roads and other infrastructure on biodiversity and ecosystems. Potential solutions are possible but they will involve serious trade-offs and the confrontation of deep misconceptions. Here, I identify some time-critical tactics to aid scientists in informing and influencing the global infrastructure debate.
, Journal of Molecular Biology, Volume 430, 20 July 2018
About 7000 rare, or orphan, diseases affect more than 350 million people worldwide. Although these conditions collectively pose significant health care problems, drug companies seldom develop drugs for orphan diseases due to extremely limited individual markets. Consequently, developing new treatments for often life-threatening orphan diseases is primarily contingent on financial incentives from governments, special research grants, and private philanthropy.
, Clinical Nutrition ESPEN, Volume 24, April 2018
Background: Older adults are at increased risk of malnutrition compared to their younger counterparts. Malnutrition screening should be conducted using a valid malnutrition screening tool. An aim of the Healthy Diet for a Healthy Life (HDHL) Joint Programming Initiative (JPI) ‘Malnutrition in the Elderly Knowledge Hub’ (MaNuEL) was to review the reported validity of existing malnutrition screening tools used in older adults.
, Clinical Microbiology and Infection, Volume 24, April 2018
Objectives: This paper review trends in emerging infections and the need for increased clinical and laboratory surveillance. Methods: Factors that contributed to the emergence of recent outbreaks have been reviewed. Known, major outbreaks over the past two decades were reviewed. Results: We identified at least four major drivers of emergent infections: (i) increasing density of the human population; (ii) stress from farmland expansion on the environment; (iii) globalization of the food market and manufacturing; (iv) environmental contamination.
, Journal of Ethnopharmacology, Volume 210, 10 January 2018
Ethnopharmacological relevance In the Peruvian Amazon, the use of medicinal plants is a common practice. However, there is few documented information about the practical aspects of their use and few scientific validation. The starting point for this work was a set of interviews of people living in rural communities from the Peruvian Amazon about their uses of plants. Protozoan diseases are a public health issue in the Amazonian communities, who partly cope with it by using traditional remedies.
, The Lancet Psychiatry, Volume 4, November 2017
Background Mental illness is one of the most rapidly increasing causes of long-term sickness absence, despite improved rates of detection and development of more effective interventions. However, mental health training for managers might help improve occupational outcomes for people with mental health problems. We aimed to investigate the effect of mental health training on managers' knowledge, attitudes, confidence, and behaviour towards employees with mental health problems, and its effect on employee sickness absence.
, Contraception, Volume 96, October 2017
Background Although abortion is legal in Thailand for a number of indications, women from Burma residing in Thailand are rarely able to access safe services. We evaluated the outcomes of a community-based distribution program that provides migrant, refugee, and cross-border women from Burma with evidence-based information about and access to misoprostol for early pregnancy termination.