Elsevier,
Overcoming Obstacles in Drug Discovery and Development
Surmounting the Insurmountable—Case Studies for Critical Thinking
2023, Pages 215-222
This content aligns with Goal 3: Good Health and Wellbeing by identifying the reactive metabolite responsible for the species-specific nephrotoxicity observed in rats dosed with efavirenz provide a framework for addressing nonclinical toxicities and clinical risk and providing a solid scientific basis for regulatory review.
Elsevier Health is launching an ambitious initiative called “The Year of the Zebra” to educate millions of current and future healthcare professionals, caregivers, researchers, patients, family members, and the general public about rare disorders.
In 2021, RELX continued to build on our strong corporate responsibility (CR) performance during the year, further improving on our key internal metrics and extending the scope of our unique contributions. This article is linked to SDGs 1,3,10,11,12,13 and 16, in line with RELX's areas of expertise.
Due to multiple cellular blocks in transcription, HIV-1 latency can only be reversed in a minor fraction of infected but potentially virus-producing CD4+ T cells from infected patients. New insights into the regulation of transcription elongation factor P-TEFb as a crucial rate-limiting step in the emergence of HIV-1 from latency may help design more effective latency reversal agents during HIV-1 infection.
This article supports SDG 15 through its review of ecologically-based farming systems.
This article ties to SDG 3. This scoping review looks at the role of place in refugee mental health.
This paper looks at the effect of the SARS-CoV2 vaccination on people living in HIV, in terms of their immune responses.
Ticks: Biology, Ecology, and Diseases, 2023, Pages 193-215
This chapter advances the UN SDG Goal 3: Good Health by covering the range of approaches to the control of tick and tick-borne diseases.
Background: In patients with cystic fibrosis (CF), thoracic morphology and its role in respiratory function is conditioned by anthropometric factors, as well as by pathological changes. While the lungs are continuously monitored, examinations of potential thoracic cage adaptations to the disease are rare. Hence, the aim of this study was to investigate thoracic configuration, and its correlation to spirometry measures over time. Methods: In total, 344 high-resolution computed tomography (HRCT) examinations from 90 patients were assessed and analysed. Those results were subsequently related to spirometry measurements performed within the same period. Results: The cohort displayed no homogenous change in thoracic configuration over time, and correlation between thoracic area and spirometry variables could not be supported statistically. Conclusions: Although the current study included a larger cohort of patients with CF compared to previous studies on thoracic morphology, no patient group-specific changes in thoracic configuration were revealed. Furthermore, no correlations between structural findings and functional respiratory measurements were found.
The articles supports SDG 13 and gives a realistic look at CO2 emissions, average temperature increases, and the role of developing and implementing sustainable technologies in solving the climate problems
