This article discusses the potential therapeutic strategy of enhancing mitophagy through rapamycin treatment to alleviate cognitive impairment in Alzheimer's disease by improving mitochondrial dysfunction and neuronal loss, suggesting a novel mechanism for the neuroprotective effects of rapamycin in AD.
This study demonstrates that electroacupuncture (EA) improves learning and memory in the 5xFAD mouse model of Alzheimer's disease, likely by enhancing functional connectivity between the hippocampus and neocortex and reducing amyloid-β protein expression and deposition. These findings suggest that EA may positively impact resting-state brain activity and connectivity, contributing to cognitive and motor function improvements in AD.
2025's World Leprosy Day: A Unified Call for Dignity and Healing
Celebration and Recognition
World Leprosy Day is commemorated each year on the final Sunday of January, promoting worldwide unity in the battle against leprosy. On January 26th, 2025, this day will occur. In India, January 30th is an important event that is observed annually to pay tribute to Mahatma Gandhi's death anniversary. Gandhi was a strong supporter of the rights and respect for individuals stricken with leprosy.
This study investigated antiviral effects in a real-world cohort of non-cirrhotic CHB patients with varying degrees of HS, assessed by transient elastography (TE) with controlled attenuation parameter (CAP).
The present article reviews the role of necroptosis, as a novel cell death pathway, in Aluminium-induced Alzheimer’s disease models in vitro and in vivo.
Systematic review on Global outbreaks of foodborne hepatitis
This Article supports SDG 3 by arguing that people under community correction supervision (probation or parole) are a large population of individuals at risk of viral hepatitis, to whom little attention has thus far been paid. Targeting hepatitis testing and treatment services at this population would be feasible and effective in reducing hepatitis incidence.
This study aims to develop novel prognostic models based on the dynamic changes in variables to predict the short-term mortality of HBV-associated ACLF (HBV-ACL)
The study forecasts AI-based innovation's impact on SDGs in 22 countries from 2022 to 2030 using System Dynamics Modeling. In most of the 22 countries studied, AI-based innovation positively affects SDGs 1, 3, and 5. For half of the countries studied, AI-based innovation positively influences SDGs 2, 4, 6–8, 11, 13, and 16–17. AI-based innovation does not positively influence SDGs 10, 12, 14–15 for most countries studied.
This chapter aligns with Goals 9 and 14 by studying the risk-based assessment methods associated with health, safety, and environmental protection of engineering structures and infrastructure, discussing how to prevent and mitigate oil and gas leaks, fires, explosions, and more.
