To understand how best to help patients and improve health during an epidemic it is necessary to have good modelling techniques and protocols.
This year’s RELX SDG Inspiration Day will bring together global AI leaders, corporate representatives, investors, government, and NGOs to explore issues, gain practical insights and be inspired to take action in support of the Global Goals. Elsevier is proud to share this special collection of articles and chapters in celebration of this event.
Elsevier,
Remington and Klein's Infectious Diseases of the Fetus and Newborn Infant (Ninth Edition), 2025, Pages 728-744.e4
This content aligns with Goal 3: Good Health. Public health programs at the governmental level are in need for prevention of the maternal-fetal transmission of these viruses and access to available antiviral therapies.
This study introduces an innovative method using DNA barcodes to accurately identify species, addressing the critical issue of trafficking invaluable medicinal plants like Trillium govanianum.
This study developed four deep learning models to identify potential Alzheimer's disease treatments from traditional Chinese medicine, specifically the Kaixinsan formula. The models successfully predicted compounds that showed significant anti-Alzheimer's activities in various experimental validations.
This article supports SDG 3 by showing that using an interactive mHealth application can reduce dementia risk factors in populations who are underserved and at increased risk.
This article looks at complications that arise from combinations of Alzheimers and osteoporosis in mouse models
This study identified key biochemical pathways and protein changes in the Alzheimer's disease (AD) human hippocampus, revealing increased expression of proteins VGF, GFAP, HSPB1, and APP, with UBC being most centrally involved, and highlighted the roles of four hub proteins (CD44, APP, ITGB2, APOE) linked to amyloid plaques and two (RPL24, RPS23) to neurofibrillary tangles, along with the impact of modified proteins on immune activation and synaptic disruption, uncovering potential therapeutic targets involving specific proteins, microRNAs, and transcription factors.
This study presents an optimized method for isolating specific neuronal and glial cell populations and extracellular vesicles (EVs) from postmortem Alzheimer's disease (AD) cortical samples, demonstrating the feasibility of using a single cryopreserved brain sample to obtain RNA-seq and protein-level data, thereby enhancing understanding of neuron/glial interactions and disease progression.
This article summarizes current biomarkers, available treatments, and future therapeutic approaches for Alzheimer's disease, discussing drug targets like Amyloid β, Tau Protein, and various other mechanisms. Additionally, it highlights the historical use of Estradiol, outcomes of trials with antioxidants and omega-3 fatty acids, and ongoing clinical trials, providing a comprehensive overview of the evolving landscape in AD research and treatment.
