Research

Elsevier, EBioMedicine, Volume 58, August 2020
Background: Microglia, the brain's principal immune cell, are increasingly implicated in Alzheimer's disease (AD), but the molecular interfaces through which these cells contribute to amyloid beta (Aβ)-related neurodegeneration are unclear. We recently identified microglial contributions to the homeostatic and disease-associated modulation of perineuronal nets (PNNs), extracellular matrix structures that enwrap and stabilize neuronal synapses, but whether PNNs are altered in AD remains controversial.
Elsevier, Thermal Science and Engineering Progress, Volume 18, 1 August 2020
This study investigated the drying behaviour of purple-speckled Cocoyam and the effect of drying temperature (40 °C, 60 °C and 75 °C), slice thickness (4 mm, 7 mm and 10 mm) and pre-treatments (blanching in boiling water for 3 min, blanching in boiling water for 3 min followed by dipping in 0.1 per cent sodium metabisulfite for 5 min) and non-pre-treated slices. The process and quality criteria under consideration included the total drying time, rehydration ratio, colour difference, browning index and specific energy consumption.
Elsevier, Thermal Science and Engineering Progress, Volume 18, 1 August 2020
Quality attributes such as moisture content, colour parameters and shrinkage of apples change undesirably during the drying process. Drying is a highly dynamic process, thus, an effective optimisation in terms of product quality and process performance requires continuous non-invasive measurement of the parameters in question.
Elsevier, Current Opinion in Endocrine and Metabolic Research, Volume 13, August 2020
Decades of population-based health outcomes data highlight the importance of understanding how environmental exposures in pregnancy affect maternal and neonatal outcomes. Animal model research and epidemiological studies have revealed that such exposures are able to alter fetal programming through stable changes in the epigenome, including altered DNA methylation patterns and histone modifications in the developing fetus and infant.
Elsevier,

Sustainable Development Strategies, Engineering, Culture and Economics, 2021, Pages 1-25

This book chapter advances SDG 11 and 13 by introducing the concepts of sustainable development. The definitions as evolved over time have been briefly discussed. The evolution of the sustainable development concepts coupled with the underling theorems, philosophy, ethics, and social responsibility has also been described. The dimensions of sustainable development along with the recent trends have also been discussed.
Elsevier, The Lancet Global Health, Volume 8, August 2020
Background: Breast cancer has distinct causes, prognoses, and outcomes and effects in patients at premenopausal and postmenopausal ages. We sought to assess the global burden and trends in breast cancer by menopausal status. Methods: We did a population-based analysis of global breast cancer incidence and mortality among premenopausal and postmenopausal women. Menopausal status was defined using age as a proxy, whereby breast cancer cases or deaths at age 50 years or older were regarded as postmenopausal.
Elsevier,

The Lancet Global Health, Volume 8, August 2020

This study supports SDG 3 and 10 by showing increased mortality due to COVID-19 in Brazil’s mixed ethnicity and Black populations and regions with lower levels of socioeconomic development, highlighting the need to better protect these vulnerable groups from the adverse effects of the COVID-19 pandemic.
Elsevier,

The Lancet Global Health, Volume 8, August 2020

This study supports SDGs 3 and 6 by suggesting that current methods of cholera control are insufficient at achieving zero transmission of Vibrio cholerae in Haiti, and that large-scale cholera vaccination campaigns are needed alongside improvements in water and sanitation for long-term cholera elimination.
Elsevier,

Cross-Cultural Family Research and Practice, 2020, Pages 249-285

Efforts to provide a normed standard for what constitutes intimate partner violence, child abuse, and neglect have clashed with attempts to recognize the impact of cultural variability on the experiences of family maltreatment. Contributing to SDGs 3 and 5, this chapter takes on this challenging intersection by answering vital questions about the operationalization of intimate partner violence and child maltreatment, including how to integrate the need for universal standards with considerations of cultural context.

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