World Alzheimer’s Day 2022

An estimated 50 million people around the world currently live with Alzheimer's disease or other dementias, dementia being a collective term for progressive syndromes that affect various expressions of cognitive function, such as memory and emotional expression. Alzheimer’s disease accounts for the majority of cases (50 to 70%, varying by country, based on Alzheimer’s Disease International and World Health Organization figures). For those directly affected and their loved ones, dementia can be a frightening experience, particularly as it is so poorly understood. However there remains little or no understanding of dementia in many, and the stigmatization and misinformation that surrounds dementia remains a global issue.

For 2022 World Alzheimer’s Day the theme Know Dementia, Know Alzheimer’s, organized annually by Alzheimer’s Disease International, focuses on diagnosis, the warning signs of dementia, with a special focus on post-diagnosis support. The aim of this international campaign is to highlight the importance of support for people living with dementia and families following a diagnosis.

 Share of direct out-of-pocket, informal care, and direct public and private health and LTC insurance costs of dementia in 2018.

The Lancet Regional Health - Europe, Volume 20, September 2022

An article on dementia and Alzheimer's disease costs, in the context of SDG 3, focusing specifically on the economic costs of care in Europe.

Experimental Eye Research, Volume 221, August 2022

This research provides the first evidence of AD-related Aβ pathology outside the brain. Lens Aβ can be noninvasively measured in vivo for early AD detection and monitoring.
PPI network analysis of potential targets of trans-UCA involved in spatial memory. (A) PPI network based on STRING database showed 39 potential targets. (B) PPI network based on Cytoscape 3.7.2 software showed 39 potential targets.

Physiology and Behavior, Volume 252, 1 August 2022

The results of this study suggest that trans-UCA facilitates spatial memory in the Y-maze test and OLR task and may offer therapeutic potential for Alzheimer's disease (AD).

The Lancet Healthy Longevity, Volume 3, June 2022

An Article on dementia risk factors, in the context of SDG 3, focusing specifically on whether cardiac multimorbidity increases dementia risk.
Screenshot from CIRCA.

Learning, Culture and Social Interaction, Volume 34, June 2022

People living with dementia are capable of managing novel activities in collaboration with other people living with dementia.
A carer (on the left) gives food to the person with dementia (on the right).

Journal of Aging Studies, Volume 61, June 2022

This article addresses supporting those with late-stage dementia to maintain quality of life.
Graphical abstract

Redox Biology, Volume 51, May 2022

This paper reveals effective etiological capabilities of theranostic F-SLOH to target and intervene multiple neuropathological changes in AD mouse models. Therefore, F-SLOH demonstrates tremendous therapeutic potential for treating AD in its early stage.

The Lancet Healthy Longevity, Volume 3, April 2022

An article on interventions for people with mild dementia, in the context of SDG 3, focusing specifically on the benefits and cost-effectiveness of the Journeying through Dementia intervention in England.

Free Radical Biology and Medicine, Volume 183, April 2022

In this review, we aim to discuss the multimodal action of genistein as an antioxidant, anti-inflammatory, anti-amyloid β, and autophagy promoter, which could be responsible for the genistein beneficial effect on Alzheimer's.