Solitary Langerhans-cell histiocytosis arising from sternum

Asian Journal of Surgery, Volume 45, Issue 7, 2022
Xian-Ying Wang, Huan Yan, Chun-Nian Ren, Li-Bing Zhang

Langerhans cell histiocytosis (LCH) is a rare disease, occurring at all ages,characterized by pathological dysplasia and aggregation of monocytes, macrophages and dendritic cells. The incidence rate of children aged 0–14 is about 3–5/100,000.1 LCH is characterized by proliferation of Langerhans cells, which usually causes pain and swelling of adjacent soft tissues, but can also be asymptomatic. Solitary sternal LCH is very rare.