Ensure healthy lives and promote well-being for all at all ages

Elsevier,

Current Opinion in Chemical Biology, Volume 65, December 2021

Intelligent data mining as a fast way to find new purposes for existing drugs.
This book chapter advances SDGs 3 and 17 by outlining the common physical impairments found in people living with dementia, as well as evidence for treatments to maintain or improve physical function and prevent falls, in both community and residential settings.
An evaluation of the pharmacological potency of 2 agents which may lead to the development of treatment for Alzheimer's.
Elsevier,

Current Opinion in Chemical Biology, Volume 64, October 2021

A review of peptide model systems used to investigate and understand the structures, biological properties, and biophysical properties of amyloid oligomers linked to diseases such as Alzheimers.
A review of recent advances in protein chemistry, biophysics, advanced imaging, and proteomics and the way they could be applied to decipher and embrace the complexity of protein aggregation and pathology formation. This may advance translational research and drug discovery in neurodegenerative diseases.
Elsevier,

Current Opinion in Chemical Biology, Volume 64, October 2021

A review of potential inhibitors of amyloid protein aggregation, one of the causes of neurodegredation.
Elsevier,

Prostaglandins and Other Lipid Mediators, Volume 156, October 2021

This review focuses on the role of 7-ketocholesterol (7KCh) mediated neurodegenerative Alzheimer’s disease with emphasis on alterations in the lipid raft microdomain. In addition, current trends in the significant therapies related to 7KCh inhibition are highlighted.
Multiple factors such genetics, metabolism, and lifestyle factors are involved in both COVID-19 and Alzheimer’s disease.
Elsevier,

Behavioural Brain Research, Volume 414, 24 September 2021

Studies have shown that the RhoA/ROCK signaling pathway can promote Alzheimer's disease and therefore, ROCK is a promising drug target in AD.
World Alzheimer's Day is an international campaign organised by Alzheimer's Disease International to raise awareness and highlight issues faced by people affected by dementia. It takes place every year on September 21st and is the focus of World Alzheimer's Month. In support of this year’s theme – ‘Know dementia, know Alzheimer's’ - Elsevier presents a curated, open access collection of over 70 journal articles and book chapters focused on shining a light on the warning signs of dementia and the importance of a timely diagnosis.

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