Diversifying preclinical research tools: expanding patient-derived models to address cancer health disparities

Elsevier, Trends in Cancer, Volume , 2022
Halmai N.B., Carvajal-Carmona L.G.

Cancer health disparities define a critical healthcare issue for racial/ethnic minorities in the USA. Key findings have led to cancer treatment improvements tailored to minority patients, but such successes have been rare. Here, we highlight how the use of patient-derived xenograft (PDX) and organoid models could resolve current blocks toward precision cancer health equity.