Elsevier, International Journal of Radiation Oncology Biology Physics, Volume 107, 15 July 2020
Purpose: Radiation therapy interruption (RTI) worsens cancer outcomes. Our purpose was to benchmark and map RTI across a region in the United States with known cancer outcome disparities. Methods and Materials: All radiation therapy (RT) treatments at our academic center were cataloged. Major RTI was defined as ≥5 unplanned RT appointment cancellations. Univariate and multivariable logistic and linear regression analyses identified associated factors. Major RTI was mapped by patient residence. A 2-sided P value <.0001 was="" considered="" statistically="" significant.="" results:="" between="" and="" a="" total="" of="" patients="" received="" rt="" whom="" were="" eligible="" for="" analysis:="" had="" interruptions="" major="" rti.="" disparities="" in="" rti="" seen="" across="" medicaid="" versus="" commercial="" insurance="" vs="" p="" low="" high="" predicted="" income="" black="" white="" race="" urban="" suburban="" treatment="" location="" on="" multivariable="" analysis="" increased="" odds="" ratio="" confidence="" interval="" those="" with="" head="" neck="" ci="" gynecologic="" lung="" cancers="" compared="" breast="" cancer.="" mapped="" to="" majority="" low-income="" neighborhoods="" rural="" regions.="" conclusions:="" radiation="" interruption="" disproportionately="" affects="" financially="" socially="" vulnerable="" patient="" populations="" maps="" high-poverty="" neighborhoods.="" geospatial="" mapping="" affords="" an="" opportunity="" correlate="" access="" neighborhood="" level="" inform="" potential="" intervention="" strategies.="">
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African American; Aged; Ancestry Group; Article; Breast Cancer; Cancer Radiotherapy; Caucasian; Cohort Analysis; Comparative Study; Confidence Interval; Continental Population Groups; Controlled Study; Demography; Diseases; Economics; Electronic Medical Record; External Beam Radiotherapy; Female; Female Genital Tract Cancer; Geospatial Mapping; Head And Neck Cancer; Health Care Disparity; Health Insurance; Healthcare Disparities; Household Income; Human; Humans; Income; Insurance, Health; Intervention Strategy; Logistic Regression; Major Clinical Study; Male; Medically Uninsured; Medicare; Metastasis; Methods And Materials; Middle Aged; Multi Variables; Multivariable Analysis; Outcome Assessment, Health Care; Personal Experience; Priority Journal; Prostate Cancer; Radiation Treatments; Radiotherapy; Residence Characteristics; Socioeconomics; Spatial Analysis; Treatment Interruption; Treatment Outcome; Vulnerable Patients; Global