Chapter 1 - Effect of plant extracts against Alzheimer’s disease

Elsevier, Plant Extracts in Neurodegenerative Diseases, First Edition, 2022, pp 1-15
Magisetty Obulesu

Alzheimer’s disease (AD) is a neurodegenerative disease (ND) most commonly seen in elderly citizens. Since oxidative stress has been found to be the major cause of AD among several etiological factors, a plethora of plant extracts with immense antioxidant efficacy has been used to combat pathological events. In this chapter, we focused on polyphenols and flavonoids and their crucial role in decreasing AD symptoms. In addition, we highlighted the neuroprotective role of various essential ingredients of plant extracts such as Icariside, Onjisaponin B, Asarones, Liquiritin, Tanshinone IIA (TIIA) and cryptotanshinone (CT), Ginsenoside Rg1, and n-Butylidenephthalide. The efficacy of green nanotechnology has also been discussed.