This study presents AlzFormer, a novel deep learning framework utilizing spatiotemporal self-attention to classify Alzheimer’s disease (AD), mild cognitive impairment (MCI), and cognitively normal (CN) individuals from structural MRI scans. By modeling MRI volumes as sequential slice-based inputs and fine-tuning a pre-trained TimeSformer model, AlzFormer achieved 94% accuracy and high class-wise F1-scores, while attention map analyses highlighted clinically relevant brain regions, demonstrating both robust performance and interpretability in multiclass AD diagnosis.
Report on a new smart delivery system designed to target and treat Alzheimer's disease more effectively, aiming to overcome the challenges of current treatments and offering a promising way to fight Alzheimer's more accurately and safely.
This article provides a comprehensive review of the use of graphene-based biosensing platforms for the early detection of Alzheimer's disease. It is found that graphene-based biosensors can detect Alzheimer's disease biomarkers at femtomolar concentrations, enabling early diagnosis before symptom onset. These sensors can also identify multiple biomarkers simultaneously in accessible biofluids like blood, saliva, and urine, enabling less invasive testing.
Pressurized metered-dose inhalers contribute substantially to the health care sector's carbon footprint due to hydrofluorocarbon propellants, whereas dry powder inhalers (DPI) have a lower environmental impact. This study compares asthma treatment strategies by assessing both clinical effectiveness and carbon emissions, demonstrating that as-needed budesonide/formoterol DPI is more environmentally sustainable and clinically comparable with other treatments.
This paper examines how climate change and environmental factors impact rheumatic diseases, introducing the concept of planetary health and the exposome as frameworks for understanding these interconnections.
In this episode of the “World We Want” podcast, Márcia Balisciano interviews Professor Jurgita Malinauskaite, Professor of law and Head of Brunel Law School at Brunel University of London. They discuss the role of law, research, and collaboration in driving sustainability, from fair competition and energy transitions to circular economy solutions, all in alignment with the UN Sustainable Development Goals.
This study measured testosterone and pre-androgens in blood, finding changes with age but not with menopause. This indicates that menopause itself is not a reason for women to need testosterone supplementation.
Celebrated annually on October 16, World Food Day is a key global event focused on raising awareness about food security and hunger. Established by the United Nations Food and Agriculture Organization (FAO) in 1979, this day highlights the ongoing challenges of hunger, malnutrition, and the need for sustainable food systems.
This viewpoint offers insights on policy to improve diet quality, that resonate not only in Bangladesh but also across other countries navigating similar transitions.
With an estimated 2 billion people worldwide suffering from iron deficiency — a condition linked to anemia, impaired childhood brain development, and higher infant mortality — researchers are racing to find more effective nutritional interventions. MIT scientists have developed a promising solution: tiny crystalline particles known as metal-organic frameworks (MOFs) that can be used to fortify everyday foods and beverages, mixed into foods such as bread or sprinkled directly into drinks like coffee or tea.
