Elsevier, Seminars in Oncology, 2025, 152352
As reported by the World Health Organization (WHO), cervical cancer ranks as the 8th most common cancer globally and the ninth leading cause of cancer death, with 661 044 new cases and 348 186 deaths reported annually. It is the most common cancer among women in 25 countries, many of which are located in sub-Saharan Africa [1]. Although the incidence of cervical cancer is expected to increase, this rise will predominantly occur in low- and middle-income countries (LMICs). In South Africa, the incidence rate of cervical cancer ranges from 22.8 to 27 per 100 000 women, significantly higher than the global average of 15.8 per 100 000 [2].
