Current Opinion in Chemical Biology, Volume 65, December 2021,
Drug repurposing aims to find new uses for already existing and approved drugs. We now provide a brief overview of recent developments in drug repurposing using machine learning alongside other computational approaches for comparison. We also highlight several applications for cancer using kinase inhibitors, Alzheimer's disease as well as COVID-19.
1 Cyclohexyl 4 [3 (1,2,3,4 Tetrahydro 5 Methoxy 1 Naphthyl)propyl]piperazine; Alzheimer Disease; Antibiotic Agent; Antineoplastic Agent; Antineoplastic Agents; Antiviral Agents; Antivirus Agent; Biology; COVID-19; Clemastine; Cloperastine; Computational Biology; Coronavirus Disease 2019; Dipyridamole; Drug Discovery; Drug Repositioning; Drug Repurposing; Human; Humans; Hydroxychloroquine; Lenalidomide; Machine Learning; Malignant Neoplasm; Neoplasm; Neoplasms; Neuroprotective Agent; Neuroprotective Agents; Nonhuman; PB28 Compound; Phosphotransferase Inhibitor; Piperazine Derivative; Piperazines; Piperidine Derivative; Piperidines; Procedures; Protein Kinase Inhibitor; Protein Kinase Inhibitors; Review; Global