Chapter 1 - Classification, risk factors, and clinical presentation diabetic neuropathy

Elsevier, Diabetic Neuropathy, 2022, Pages 1-9
Dilek Gogas Yavuz

Diabetic neuropathy is the most common and debilitating complication that occurs in nearly 50 percent of patients with diabetes. Diabetic neuropathy can cause significant morbidity and mortality. There is no universally accepted classification for diabetic neuropathies, and a classification based upon the clinical manifestation is most preferred in clinical practice. The primary forms are Distal symmetric polyneuropathy and Autonomic neuropathy. Hyperglycemia, duration of diabetes, age, and cardiovascular associated risk factors (obesity, dyslipidemia, hypertension) are typical for diabetic neuropathy.

Although the diagnosis of diabetic neuropathy depends on clinical symptoms and signs, it is challenging to diagnose due to the lack of a consensus for the definition and clinical assessment criteria.