Musculoskeletal disorders are characterized by pain, weakness, stiffness, mental disorders, a decrease in functionality which often resulted in chronic health disturbances that impact negatively on social relationships. The peripheral nervous system (PNS) is involved in every syndrome or injury related to the musculoskeletal system, such as low back-related leg pain or neck-related arm pain. Thus, the manual therapy that targets the nervous system could be an interesting method for the treatment of pain. Neural mobilization (NM) techniques were employed for the diagnosis and treatment of the mechanical and physiological properties of the PNS. Strong evidence supported that NM has immediate mechanical hypoalgesic effects in individuals with cervicobrachial pain, carpal and cubital tunnel syndromes, low back pain, and lower limb musculoskeletal disturbances related to neural tissue conditions and evidence the potential of this non-pharmacological intervention, without adverse secondary effects of drugs.
Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics, Volume , 1 January 2021,