Introduction and Objectives: We initiated this multicenter study to integrate important risk factors to create a nomogram for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) for clinician decision-making. Patients and Methods: Between April 2011 and March 2022, 2281 HCC patients with an HBV-related diagnosis were included. All patients were randomly divided into two groups in a ratio of 7:3 (training cohort, n = 1597; validation cohort, n = 684). The nomogram was built in the training cohort via Cox regression model and validated in the validation cohort.
This Review supports SDGs 3 and 13 by synthesizing the recent evidence on whether and how climate change, manifested in meteorological fluctuations, extreme weather events, and long-term global warming, influences the epidemic dynamics of viral respiratory infections, including spatiotemporal distribution of seasonal epidemic, disease outbreaks, and pandemics.
Tuberculosis is a major contributor of morbidity and mortality in people living with HIV. This study investigates treatment of coinfection with the current first-line treatments for both infections.
Female sex workers are a key population for HIV control. This study uses data from Zimbabwe's national sex worker programme to shed light on HIV outcomes in this important population.
This article supports SDG 3 by evaluating the outcomes of early liver transplantation for alcohol-associated hepatitis.
This content ties into the SDG goal by exploring music and how it can best be used to help decrease agitation in patients with Alzheimer's and related dementias
This paper evaluates new indications and key mechanism of a clinically approved drug Bazi Bushen capsule for treatment of Aizheimer's disease using network pharmacology approach.
This paper looks at the role of the circadian clock and the regulation of HIV-1 replication.
This Viewpoint supports SDG 3 by discussing how HIV services and primary health care services can be integrated in order to improve HIV outcomes over standalone, siloed HIV care. The reports discusses existing models of integration and the various elements of successful integration.
Research on mitochondrial homeostasis is promising for the treatment of early AD.
