Research

Depression in Sub-Saharan Africa

Elsevier,

IBRO Neuroscience Reports, Volume 12, June 2022

This review attempts to shed more light on the prevalence of depression in Sub-Saharan Africa (SSA), its pathophysiology, risk factors, diagnosis and the experimental models available to study depression within the sub-region. It also evaluates the contribution of the sub-region to the global research output of depression as well as bottlenecks associated with full exploitation of the sub region’s resources to manage the disorder.
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SDG:

Goal 10: Reduced inequalities

Tags:

Health and wellbeing, Africa

Investigating the effect of Mindfulness-Based Stress Reduction on stress level and brain activity of college students

Elsevier,

IBRO Neuroscience Reports, Volume 12, June 2022

Financial constraints usually hinder students, especially those in low-middle income countries (LMICs), from seeking mental health interventions. Hence, it is necessary to identify effective, affordable and sustainable counter-stress measures for college students in the LMICs context. This study examines the sustained effects of mindfulness practice on the psychological outcomes and brain activity of students.
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SDG:

Goal 3: Good health and well-being; Goal 10: Reduced inequalities

Tags:

Health and wellbeing, Global

Liposomes: An emerging carrier for targeting Alzheimer's and Parkinson's diseases

Elsevier,

Heliyon, Volume 8, June 2022

This review highlights the role of liposomes in delivering drugs across blood-brain barrier which has been seen to reducing the pathogenesis of Alzheimer's disease (AD), Parkinson's disease (PD).
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SDG:

Goal 3: Good health and well-being

Tags:

Health and population; Health and wellbeing; Science, Global

Covid-19 vaccine immunogenicity in people living with HIV-1

Immunogenicity in each study group. Immunogenicity (anti-RBD IgG response) was measured by ELISA and reported in RLU (relative luminescence units) normalized to CR3022.
Elsevier,

Vaccine, Volume 40, 9 June 2022

COVID-19 vaccine efficacy has been evaluated in large clinical trials and in real-world situation. Although they have proven to be very effective in the general population, little is known about their efficacy in immunocompromised patients.
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SDG:

Goal 3: Good health and well-being; Goal 10: Reduced inequalities

Kaposi's sarcoma-associated herpes virus-derived microRNA K12–1 over-activates the PI3K/Akt pathway to facilitate cancer progression in HIV-related gastrointestinal Kaposi's sarcoma

Elsevier,

SLAS Discovery, Volume 27, June 2022

Understanding the pathogenesis that leads to carcinogenesis of HIV-related gastrointestinal KS is essential for the treatment of diseases related to KSHV infection. This study strived to evaluate the effect of miR-K12–1 on the progression of HIV-related gastrointestinal KS.
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SDG:

Goal 3: Good health and well-being
Global

HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect

Elsevier,

Antiviral Research, Volume 202, June 2022

Nelfinavir is an HIV protease inhibitor that has been widely prescribed as a component of highly active antiretroviral therapy, and has been reported to exert in vitro antiviral activity against SARS-CoV-2. We here assessed the effect of Nelfinavir in a SARS-CoV-2 infection model in hamsters. 
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SDG:

Goal 3: Good health and well-being; Goal 10: Reduced inequalities
Global

Provider preferences for anal cancer prevention screening: Results of the International Anal Neoplasia Society survey

Elsevier,

Tumour Virus Research, Volume 13, June 2022

This study explores provider preferences regarding anal cancer screening indications, initiation age, tools, and referral threshold to high resolution anoscopy (HRA). Although consensus was lacking with regard to specific screening initiation age, more respondents recommended younger initiation ages for men who have sex with men (MSM) living with HIV (LWH) compared with MSM not LWH (p
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SDG:

Goal 3: Good health and well-being; Goal 10: Reduced inequalities
Global

Loneliness in Older Adults - Chapter 7: Design of intervention in programs, accompaniment actions, and prevention of loneliness in the elderly

Elsevier,

Loneliness in Older Adults
Effects, Prevention, and Treatment
2022, Pages 143-165

This chapter takes research on loneliness in elderly and applies it to designing intervention programs to help prevent loneliness.
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SDG:

Goal 3: Good health and well-being

Tags:

Health and population; Health and wellbeing, Global

Oral human papillomavirus prevalence, persistence, and risk-factors in HIV-positive and HIV-negative adults

Alluvial plots denote transitions in oral HPV infection status (any genotype) over the first four study visits in a) HIV+ and b) HIV- participants who had at least 2 valid HPV tests before loss to follow up or completion of 4th visit.
Elsevier,

Tumour Virus Research, Volume 13, June 2022

HIV has been shown to increase the likelihood of oral HPV infection. In this study, we evaluated the risk of oral HPV in HIV infected patients compared with HIV-negative controls.
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SDG:

Goal 3: Good health and well-being; Goal 10: Reduced inequalities

Tags:

HIV, Global

Perceptions of HIV cure and willingness to participate in HIV cure-related trials among people enrolled in the Netherlands cohort study on acute HIV infection

Elsevier,

Journal of Virus Eradication, Volume 8, June 2022

This research highlights the need for thorough informed consent procedures with assessment of comprehension and exploration of personal motives prior to enrollment in cure-related trials
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SDG:

Goal 3: Good health and well-being; Goal 10: Reduced inequalities

Tags:

HIV, Global

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