Africa

An estimated 50 million people around the world currently live with Alzheimer's disease or other dementias, dementia being a collective term for progressive syndromes that affect various expressions of cognitive function, such as memory and emotional expression. Alzheimer’s disease accounts for the majority of cases (50 to 70%, varying by country, based on Alzheimer’s Disease International and World Health Organization figures).

This book chapter advances SDG #3 and #10 by focusing on an emblematic delayed-onset pathology often seen after traumatic brain injury—Alzheimer’s disease—and explain its relationship with chronic traumatic encephalopathy.
This book chapter advances SDG #3 and #10 by focusing on polyphenols and flavonoids and their crucial role in decreasing AD symptoms. In addition, it highlights the neuroprotective role of various essential ingredients of plant extracts such as Icariside, Onjisaponin B, Asarones, Liquiritin, Tanshinone IIA (TIIA) and cryptotanshinone (CT), Ginsenoside Rg1, and n-Butylidenephthalide. The efficacy of green nanotechnology are also discussed.
Contamination of urban-garden vegetables with potentially toxic elements is a great problem in developing countries. This study assessed the level of PTEs (Cu, Pb, Cr and Cd) in market-sold vegetables in southwest Nigeria and evaluated the estimated daily intake (EDI) to understand the health implications.
Sustainable wood-based design solutions necessarily presuppose economically, socially, and environmentally reliable sources of wood use for any future designs. However, increasingly unsustainable effects from climate extremity are now prompting the search for alternative forms of use that avoid or forestall those effects.
The Zambezi Riparian Region (ZRR) is a lifeline and home to ∼40 million people who depend heavily on the river basin for their livelihood. It also furnishes 8 of its riparian countries with goods and services on which hydropower production and food security anchor. The sustainability of the ZRR is threatened by extreme climate events. Here, we interrogate consecutive dry days (CDDs), an effective metric of extreme climatic events with implications on drought-driven water availability. We use ensemble empirical mode decomposition (EEMD) to understand CDDs.

Exercise to Prevent and Manage Chronic Disease Across the Lifespan, 2022, Pages 413-421

This book chapter advances SDG #3 and #10 by outlining the pathophysiology associated with Alzheimer’s disease and provide an overview of the impact of exercise programs on cognition, physical functional abilities, behavioral, and psychological symptoms and quality of life.

Neurobiology of Brain Disorders (Second Edition), Biological Basis of Neurological and Psychiatric Disorders, 2022, Pages 313-336

This book chapter advances SDG #3 and #10 by reviewing several key topics that influence our understanding of pathogenic mechanisms and lead to the identification of novel therapeutic strategies. These include the diagnostic spectrum of MCI and AD, genetic risk alleles associated with late-onset AD, structures of gamma-secretase and tau, imaging and fluid biomarkers, the role of microglia and neuroinflammation, and novel animal models of AD.
Establishing sustainable training to strengthen human resources for health for children's nursing in Africa requires stakeholders to navigate complex pathways spanning multiple regulatory systems and sectors. Incomplete stakeholder insight threatens long-term sustainability of new training programmes.
This book chapter advances SDG #3 and #10 by presenting drug delivery systems based on nanotechnology to treat Alzheimer’s disease.

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