Elsevier,
The Lancet, Volume 400, 29 October 2022
This Article supports SDGs 3 and 6 by demonstrating that polio environmental surveillance by testing wastewater samples is a valuable tool for tracking the distribution of polio and non-polio enteroviruses, and could be instrumental for global poliovirus elimination efforts.
Journal of Allergy and Clinical Immunology, Volume , 2022
The lung is a crucial immune organ continuously exposed to the external environment. Genetic defects that impair immune function, called inborn errors of immunity (IEI), often have lung disease as the initial and/or primary manifestation. Common types of lung disease seen in IEI include infectious complications and a diverse group of diffuse interstitial lung diseases.
Elsevier, Clinical Imaging, Volume 90, October 2022
Several studies of adult-onset multiple sclerosis (AOMS) patients have demonstrated that spinal cord volume loss is associated with disease progression and clinical disability; however, complementary studies of young patients with pediatric-onset multiple sclerosis (POMS) are lacking. In the context of SDG Goal 3, this retrospective study aimed to assess spinal cord volume in POMS patients compared with that in healthy controls.
Elsevier, Preventive Medicine Reports, Volume 29, October 2022
People with any disabilities accounted for a quarter of total deaths. People with disabilities had higher average ages and poor economic conditions. All disability types presented higher mortality rates and lower life expectancy. The major causes of death differed according to the type of disability.
Elsevier,
eClinicalMedicine, Volume 52, October 2022
This Article supports SDG 3 and 5 by highlighting a need for greater involvement of in-country authors on research examining a wider range of gendered COVID-19 impacts, as well as increased representation of diverse topics and publications related to COVID-19 and women's well-being focused on lower income countries.
Redox Biology, Volume 56, October 2022
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disorder characterized by progressive muscle weakness. Adenine nucleotide translocator 1 (ANT1), the only 4q35 gene involved in mitochondrial function, is strongly expressed in FSHD skeletal muscle biopsies. However, its role in FSHD is unclear. In this study, we evaluated ANT1 overexpression effects in primary myoblasts from healthy controls and during Xenopus laevis organogenesis. We also compared ANT1 overexpression effects with the phenotype of FSHD muscle cells and biopsies.
![Overview of brain [64Cu]-ATSM retention and mitochondrial abnormalities in cells from Huntington's disease carriers, at premanifest and manifest disease stages, and in presymptomatic YAC128 mice.](https://sdgresources.relx.com/sites/default/files/mitochondrial_and_redox_modifications.jpg "Overview of brain [64Cu]-ATSM retention and mitochondrial abnormalities in cells from Huntington's disease carriers, at premanifest and manifest disease stages, and in presymptomatic YAC128 mice.")
Redox biology, Volume 56, 1 October 2022
Deficits in mitochondrial function and redox deregulation have been attributed to Huntington's disease (HD). However, whether these changes occur in early stages of the disease and can be detected in vivo is still unclear. In this article, the authors analysed changes in mitochondrial function and production of reactive oxygen species (ROS) at early stages and with disease progression.
