Based on current studies, the incidence of Ewing sarcoma (ES) varies significantly by race and ethnicity, with the disease being most common in patients of European ancestry. However, race/ethnicity has generally been self-reported rather than formally evaluated at a population level using DNA evidence. Additionally, mitochondrial dysfunction is a hallmark of ES, yet there have been no reported studies of mitochondrial genetics in ES. Thus, we evaluated both the mitochondrial and nuclear ancestries of 420 pediatric ES patients in the United States using whole-genome sequencing.
This Article supports SDG 3 and 5 by demonstrating the need to better understand the roles that male partners play in encouraging or discouraging care-seeking behaviours during pregnancy and the postpartum period.
This chapter advances the UN SDG Goal 3: Good Health and Goal 10: Reduced Inequalities by outlining the approaches that can be broadly applied to improve health equity and reduce disparities in perioperative care.
Elsevier,

Biochimica et Biophysica Acta - Molecular Basis of Disease, Volume 1868, 1 November 2022

Infographic showing how sex bias and omission exists in Batten disease research
Batten Disease is a rare disease. This reviews highlights the existing sex bias and omissions in Batten Disease research.
This chapter advances the UN SDG Goal 3: Good Health and Goal 10: Reduced Inequalities by reviewing several patient, hospital, and community-based factors that promote racial and gender disparities in sepsis.
Elsevier,

Clinics in Liver Disease, Volume 26, Issue 4, November 2022, Pages 571-582

This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by outlining the state-of-the-art regarding the genetic architecture of PBC and thoughtful reflections on the limitations of current genetic methods
Elsevier,

Hand Clinics, Volume 38, Issue 4, November 2022, Pages 385-392

This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by highlighting advanced imaging and wrist arthroscopy for accurate staging and selecting of appropriate treatment.
Elsevier,

The Lancet Planetary Health, Volume 6, October 2022

This Personal View supports SDGs 3 and 13 by reviewing the ways that climate risks affect all aspects of the COVID-19 pandemic, including transmission, perception, and response. The authors highlight the importance of considering climate risks in relation to COVID-19 response measures.
Negative attitudes toward mental illness and treatment are attributed to a lack of or inaccurate mental health knowledge.
Background: There is an urgent need to reduce the burden of depression among older adults in low-income and middle-income countries (LMICs).

Pages