Global

Making Waves: A research agenda for supporting a WASH sustainability transformations approach to climate change

Elsevier, Water Research X, Volume 28, 1 September 2025
This perspective argues that current WASH resilience strategies in low- and middle-income countries are insufficient, emphasizing the need for a transformative approach that addresses broader socio-environmental impacts of climate change. It proposes a research agenda focused on identifying which WASH systems to transform, the timing, leadership roles, and methods for monitoring and evaluating these transformations to achieve sustainable outcomes.
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Climate Change, Global

Cement and concrete as carbon sinks: Transforming a climate challenge into a carbon storage opportunity

Elsevier, Carbon Capture Science and Technology, Volume 16, September 2025
This paper highlights the potential of engineered mineral carbonation to transform cement and concrete into effective carbon sinks by enhancing CO2 storage while maintaining material performance, emphasizing the use of alkaline industrial residues and carbonatable binders. It proposes a strategic roadmap integrating scientific innovation, regulation, and carbon accounting to promote climate-positive construction.
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Climate Change, Global

County-level modeled extreme heat risk and premature all-cause mortality related to cardio-kidney-metabolic syndrome in the United States: A cross-sectional analysis

Elsevier, American Journal of Preventive Cardiology, Volume 23, September 2025
This study examined the link between extreme heat waves and age-adjusted cardio-kideny-metabolic mortality in US counties from 2010 to 2019
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Health and wellbeing, Global

Cloud-based SOC optimization for predictive energy management and zero emission zone compliance in PHEVs

Elsevier, eTransportation, Volume 25, September 2025
The article proposes a predictive control strategy for Plug-in Hybrid Electric Vehicles (PHEVs) that utilizes route information from digital map providers to enable electric driving within zero-emission zones. The study develops a supervisory control with Dynamic Programming in the cloud to calculate an optimal State of Charge (SOC) trajectory, which is then used to guide the rule-based controller in the vehicle.
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Energy, Global

Association Between Thyroid Dysfunction and Alzheimer's Disease: Insights From the U.S. Mortality Database

Elsevier,

Endocrine Practice

Volume 31, Issue 9, Supplement, September 2025, Page S193

 

Evidence from preclinical research suggests that dysfunction in thyroid hormones may increase ?-amyloid levels and tau phosphorylation, 2 hallmark features of Alzheimer's Disease(AD). This study showed a strong association between hypothyroidism and AD mortality.

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Health and wellbeing, Global

Combating Wildlife Trafficking with the Power of Collaboration

LexisNexis Risk Solutions
An image of the front cover of the white paper report featuring an African Elephant

Learn how to help prevent wildlife trafficking by utilising partnerships and data in this joint LexisNexis Risk Solutions and United for Wildlife report.

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Wildlife Crime; Biodiversity and ecosystems, Global

RELX Environmental Challenge 2025 shortlist announced

RELX
A youn g child watching anothether child demonstrating the use of a water filter

RELX Environmental Challenge 2025: four shortlisted projects to bring safe water and sanitation to communities around the world

The RELX Environmental Challenge 2025 shortlist features four innovative projects that provide sustainable access to safe water and improved sanitation.  The RELX Environmental Challenge prioritises replicable, scalable, sustainable and innovative solutions. They must also have practical applicability and involve local communities and other key stakeholders.

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Sustainable Water Management; Water and sanitation; Water; Water Resource Management, Global

Alzheimer disease: Amyloid peptide controversies and challenges of anti-Aβ immunotherapy

Elsevier,

Journal of Pharmacology and Experimental Therapeutics, Volume 392, August 2025
This review discusses the dual role of amyloid-beta (Aβ) in Alzheimer's disease (AD). While Aβ accumulation is a hallmark of AD pathology, soluble Aβ also plays a neuroprotective role in regulating synaptic plasticity and memory. The review explores the potential of anti-Aβ immunotherapy as a treatment strategy, highlighting the need to balance targeting toxic Aβ species while preserving the physiological functions of Aβ.`
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Health and wellbeing; Health and population, Global

Gray matter and white matter functional connectivity changes induced by rTMS concurrent with cognitive training in Alzheimer's disease

Elsevier,

Brain Research Bulletin, Volume 228, August 2025
This study investigated how repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training affects functional connectivity in both gray matter and white matter in patients with mild to moderate Alzheimer’s disease. Results showed that rTMS modulated activity in key brain regions, particularly within the limbic system, with changes in white matter connectivity correlating with cognitive improvements.
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Health and wellbeing; Health and population, Global

AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy

Elsevier,

Pharmacological Research, Volume 218, August 2025
This article describes the discovery and characterization of FJMU1887, a novel brain-penetrant small-molecule inhibitor of Galectin-3 (Gal-3) identified through an AI-driven drug discovery platform. FJMU1887 demonstrated potent anti-inflammatory effects, reduced Aβ pathology, and improved cognitive function in Alzheimer's disease mouse models, highlighting its therapeutic potential for the treatment of Alzheimer's disease.
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Health and population; Health and wellbeing, Global

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