The findings in the paper imply that mitochondria may play an important role in brain resilience, and targeting mitochondria may open a new door to Alzheimer's Disease prevention and therapy.
This paper conducts a scoping review of research on the involvement of the glymphatic system in Alzheimer's disease-related sleep disturbances, finding that sleep disturbances impact protein aggregation and toxicity, glymphatic sequelae in sleep-disordered breathing, circadian dysregulation, and potential interventions, thus providing insight into the role of sleep disturbances in AD pathogenesis through glymphatic disruption.
Elsevier,
Measurement: Journal of the International Measurement Confederation, Volume 226, 28 February 2024
This paper seeks to contribute to pipeline leakage detection research through collecting and simulating leakage signals under different pressure strengths by combining experiments with numerical simulation. The findings point towards better detection in a real noise environment. Such research is vital in the context of increasing worldwide demand for water and insufficient water supply caused by pipeline leakage.
The solvents used during the production of heparin cause air and water pollution. One of the steps to achieve sustainable kidney care is to find a green alternative to heparin.
This chapter aligns with Goals 9, 11, 12 by emphasizing the responsible disposal of toxic building materials and providing guidance on selecting materials that have a positive effect on the health of occupants and the environment.
The United Nations urges governments to promote sustainable, healthy diets to combat undernutrition, obesity, and climate change. This paper examines policy insights from high-income countries (HICs) and their applicability to low- and middle-income countries (LMICs). Alternative proteins (AP) should be affordable, locally sustainable, and culturally acceptable. Food-based dietary guidelines (FBDGs) should guide AP product development, ensuring they complement traditional proteins. Harmonizing multisectoral policies is crucial for LMICs to achieve a protein transition and food systems transformation by 2050.
This study underscores the importance of recognizing and respecting diverse worldviews, knowledge systems, and values in addressing global challenges like biodiversity loss and climate change. By providing a framework that emphasizes understanding onto-epistemological assumptions and power dynamics, the research offers principles to guide more inclusive and respectful engagement with diverse perspectives, aligning with the goals of the International Day of Indigenous Peoples to promote cultural diversity and indigenous knowledge in conservation efforts.
The integration of comprehensive digital twins in laboratory environments heralds a paradigm shift, enabling a level of automation and data management previously unattainable. This integration promises to enhance the efficiency and scope of self-driving laboratories and pave the way for creating a general “artificial intelligence (AI) scientist” with universal capabilities.
The Planetary Health Diet Index (PHDI) is a novel measure adapted to quantify alignment with the dietary evidence presented by the EAT-Lancet Commission on Food, Planet, Health. This review aimed to examine how population-level health and sustainability of diet as measured by the PHDI changed from 2003 to 2018, and to assess how PHDI correlated with inadequacy for nutrients of public health concern (iron, calcium, potassium, and fiber) in the United States. Although there have been positive changes over the past 20 years, there is substantial room for improving the health and sustainability of the United States diet. Shifting diets toward EAT-Lancet recommendations would improve nutrient adequacy for iron, fiber, and potassium. Policy action is needed to support healthier, more sustainable diets in the United States and globally.
