Global

An effective response to climate change demands rapid replacement of fossil carbon energy sources. This must occur concurrently with an ongoing rise in total global energy consumption. While many modelled scenarios have been published claiming to show that a 100% renewable electricity system is achievable, there is no empirical or historical evidence that demonstrates that such systems are in fact feasible. Of the studies published to date, 24 have forecast regional, national or global energy requirements at sufficient detail to be considered potentially credible.
To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein and Beta-secretase (APP:BACE), or in flies expressing human tau. The ubiquitous expression of APP:BACE or human tau disrupted sleep. The sleep deficits could be reversed and sleep could be enhanced when flies were administered the GABA-A agonist 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridine-3-ol (THIP).
Elsevier, Neurobiology of Sleep and Circadian Rhythms, Volume 2, 2017
Sleep disorders are prevalent in Alzheimer's disease (AD) and a major cause of institutionalization. Like AD pathology, sleep abnormalities can appear years before cognitive decline and may be predictive of dementia. A bidirectional relationship between sleep and amyloid β (Aβ) has been well established with disturbed sleep and increased wakefulness leading to increased Aβ production and decreased Aβ clearance; whereas Aβ deposition is associated with increased wakefulness and sleep disturbances. Aβ fluctuates with the sleep-wake cycle and is higher during wakefulness and lower during sleep.
This content aligns with Goal 3: Good Health as well as Goal 10: Reduced Inequalities by discussing insights into the regulation and induction of bnAbs based on the use of KI models.

The sustainability of water resources depends on the dynamic interactions among the environmental, technological, and social characteristics of the water system and local population. These interactions can cause supply-demand imbalances at diverse temporal scales, and the response of consumers to water use regulations impacts future water availability. This research develops a dynamic modeling approach to simulate supply-demand dynamics using an agent-based modeling framework that couple models of consumers and utility managers with water system models.

Elsevier,

Procedia Manufacturing, Volume 8, 2017

Sustainable manufacturing extends beyond the manufacturing process and the product, to include the supply chain, across multiple product life-cycles as well as end-of-life considerations. Companies can gain a competitive advantage by applying sustainability manufacturing for environmental friendlier products and operations. Industry 4.0 sets new requirements for becoming a sustainable manufacturer where data management, the Internet of Things and extended product service systems are tightly linked with traditional manufacturing processes.

Elsevier,

Renewable and Sustainable Energy Reviews, Volume 71, 2017

In this paper, five most emerging renewable energy sources are analyzed. These emerging renewables are either special or advanced forms of the mainstream energy sources (solar, wind, geothermal, biofuels, biomass, and hydro) or brand new technologies. The five emerging renewable technologies discussed in this paper include marine energy, concentrated solar photovoltaics (CSP), enhanced geothermal energy (EGE), cellulosic ethanol, and artificial photosynthesis.

Elsevier,

The Psychology of Gender and Health: Conceptual and Applied Global Concerns, 2017, Pages 343-361

This chapter advances SDG 5 on gender equality by considering the origins of mainstreaming as a national policy initiative in England, describing the initiatives promoted and reflecting on both the progress that was made and its limitations.
Elsevier,

Physical Activity and the Aging Brain, Effects of Exercise on Neurological Function, 2017, Pages 141-150

This chapter addresses goal 3 by examining the role that exercise and physical activity play on Alzheimer’s Disease.

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