This Article supports SDG 3 by focusing on pregnant and postpartum women with HIV and assessing the risk factors for adverse postpartum outcomes and examining which factors can be addressed to support breastfeeding in resource-rich settings.
This Article supports SDG 3 by showing that international transmission of hepatitis C virus has occurred in recent years among men who have sex with men. This suggests that international coordination will be needed for microelimination in this population.
Using brain tissue from donors with Alzheimer's disease, Anderson et al. identify new links between gene regulation and disease. These regulators could represent future clinical targets or disease markers for Alzheimer's diagnosis and treatment.
Population-based surveys are expensive and time consuming. By determining state-level seropositivity using national testing service data and a Bayesian linear model, a map of HIV prevalence was generated across the whole of Nigeria. By identifying the areas in which HIV is most prevalent interventions can be targeted. This less resource intense Bayseian method allows for national monitoring of HIV prevalence.
Adverse Childhood Experiences and their Life-Long Impact, 2023, Pages 207-242
This content aligns with Goal 3: Good Health as well as Goal 17: Partnership for the goals by reviewing the effects of trauma has on a child including psychological and biological.
This study observes that oxidative dame in Alzheimer's Diseases is a pathogenic mechanism at the cell-tissue level.
In vivo triple transgenic AD mouse model brains and retinas showed hypoxic vessels expressing hypoxyprobe and HIF-1α. In in vitro OGD-treated endothelial cells, HIF-1α upregulated NADPH oxidase (NOX) (i.e., Nox2, Nox4). NLRP1 protein was promoted by OGD, and such effect was blocked by downregulation of Nox4 and HIF-1α. Hypoxic endothelial cells of AD brains and retinas markedly expressed NLRP1, ASC, caspase-1, and interleukin-1β (IL-1β). Chronic hypoxia in microvascular endothelial cells leads to HIF-1α-NLRP1 circuit in AD.
Background: Air pollution, road traffic noise, and green space are correlated factors, associated with risk of stroke.
This study links multiple models for a comprehensive assessment of the economic-environmental-health co-benefits of renewable energy development in China. The results show that developing renewable energy can avoid 0.6 million premature mortalities, 151 million morbidities, and 111 million work-loss days in 2050.
This content aligns with Goal 3: Good Health and Wellbeing by discussing the medical applications and limitations of five US Food and Drug Administration–approved INSTIs for the treatment of HIV/AIDS and preexposure prophylaxis for HIV-1.
