The impact of a military conflict on the mental health of affected communities is profound. Elsevier would like to offer a curated list of publicly available journal articles in order to support primary care providers, psychologists, social workers, teachers, carers, and any community members working with affected groups, in mental health support and treatment in connection to war, trauma and migration.
The lung compartments affected by pulmonary manifestations of IEI include the airways, alveolar space, interstitial space, vasculature, and the pleural space
The lung is a crucial immune organ continuously exposed to the external environment. Genetic defects that impair immune function, called inborn errors of immunity (IEI), often have lung disease as the initial and/or primary manifestation. Common types of lung disease seen in IEI include infectious complications and a diverse group of diffuse interstitial lung diseases.
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disorder characterized by progressive muscle weakness. Adenine nucleotide translocator 1 (ANT1), the only 4q35 gene involved in mitochondrial function, is strongly expressed in FSHD skeletal muscle biopsies. However, its role in FSHD is unclear. In this study, we evaluated ANT1 overexpression effects in primary myoblasts from healthy controls and during Xenopus laevis organogenesis. We also compared ANT1 overexpression effects with the phenotype of FSHD muscle cells and biopsies.
This Article supports SDG 3 and 5 by highlighting a need for greater involvement of in-country authors on research examining a wider range of gendered COVID-19 impacts, as well as increased representation of diverse topics and publications related to COVID-19 and women's well-being focused on lower income countries.
Fig. 2. The indicator- and domain-wise contributions to disempowerment in agency, by sex and FAARM intervention group.
This Study supports SDG 5 and 3 by examining the role of improved women's agency on the pathway from the intervention to nutritional impacts.
Overview of brain [64Cu]-ATSM retention and mitochondrial abnormalities in cells from Huntington's disease carriers, at premanifest and manifest disease stages, and in presymptomatic YAC128 mice.
Deficits in mitochondrial function and redox deregulation have been attributed to Huntington's disease (HD). However, whether these changes occur in early stages of the disease and can be detected in vivo is still unclear. In this article, the authors analysed changes in mitochondrial function and production of reactive oxygen species (ROS) at early stages and with disease progression.
This Article supports SDG 3 by estimating the impacts of the centralisation of specialist cancer services, focusing on travel time, equity of access, outcomes, and hospital workload. Using rectal cancer surgery centres as an example the authors found increases in travel times but reductions in readmission rates.
The article suggests actions to reduce the negative effect of pandemics on the healthcare workers in future situations, based on lessons learnt from COVID19.
This content aligns with Goal 10: Reduced Inequalities by exploring how social factors such as access to housing, employment, education, and healthcare contributed to the inequitable impacts of COVID-19.
This Article supports SDGs 3 and 16 by measuring the rate of heart transplantation among Black and White waitlist candidates. The findings suggest that transplantation rates, as well as the rate of delisting for death or clinical deterioration, has worsened for Black candidates compared with White candidates, and that the causes for this disparity require further study.