This content aligns with Goal 3: Good Health by demonstrating how advancements in 3D printing (3DP) technology enhance medical service delivery by creating customized prosthetics, implants, and equipment that can significantly improve health outcomes for individuals, particularly para-athletes and those with limb loss. By emphasizing the benefits of personalized medical devices and the potential for improved activities of daily living, the chapter highlights the importance of innovative solutions in healthcare. Additionally, it supports Goal 10: Reduced Inequalities by advocating for accessible and customized technologies that empower para-athletes and individuals with disabilities, promoting equity in sports and medical care and ensuring that all individuals have the opportunity to participate fully in both athletic and everyday activities.

International Youth Day 2025

International Youth Day (IYD) is dedicated to drawing attention to the cultural and legal issues surrounding youth. Established by the United Nations in 1999, this day serves as a platform for governments and organizations to address the challenges faced by young people and to recognize their contributions to global development. Observed annually on August 12th, IYD encourages activities that promote awareness, dialogue, and action on youth-related issues.

The Significance of Youth

This study aimed to examine relationships among eating frequency, timing and time window, and cognitive performance and novel Alzheimer disease (AD) biomarkers in cognitively healthy and mildly cognitively impaired middle-aged and older adults. It concluded that an eating pattern characterized by less frequent eating and/or by earlier times is present in individuals with worse cognitive performance. The results shed light on the relevance of temporal eating patterns as potential early markers of behavioral or metabolic changes related to AD pathology.

Every year, 10 million people develop dementia, most commonly Alzheimer's disease (AD), and despite limited therapies and no prevention for cognitive decline, this review offers a neuroimmunological perspective on AD progression, focusing on the role of the NLRP3 inflammasome, its brain triggers, and the potential impact of various NLRP3 inhibitors currently under investigation in preclinical and clinical trials.