Global

To further understand asthma with recurrent exacerbations (ARE) and its potential influential factors, Dr. Rachel Miller and Dr. Christine Cole Johnson and colleagues leveraged the Environmental Influences on Child Health Outcomes (ECHO)’s nationwide platform with data collected across 60 cohorts. The overall incidence rate for ARE among children was 6.1 per 1000 person-years and was highest for children aged 2-4 years, self-identified Black children, children born from 2000-2009 vs. the previous or subsequent decades, and for those with a parental history of asthma. The importance of these factors suggests substantial impacts of environmental exposures that may change over time in the development of ARE.