Nanotechnology provides an emerging potent alternate mode of cancer therapy. Nanomaterials dispersion or solubility is of particular concern in utilising their full potential applications in biomedical fields. PEGylation of nanomaterials is considered to provide products with stealth properties, and physiological environment with no obvious adverse effects. The purpose of this work was to develop a sustainable one-step method for fabrication of hierarchical microspheres of PEGylated MoS 2 nanosheets using a stoichiometric ratio of Mo(VI) and thiourea.
Drawing on discussions with Kenyan, Mexican and British teachers, this paper reports on emotional responses to international socio-economic inequality. Emotional regimes are explored to identify what ‘appropriate’ responses to inequality are in a variety of local and national contexts. These include rural and urban settings, and social milieus ranging from elite to deprived. Politeness, hand-wringing and humour can create a protective distance; while sadness, anger and hope for change connect with the issue of inequality and challenge the associated injustices.
In February, 2016, WHO released a report for the development of national action plans to address the threat of antibiotic resistance, the catastrophic consequences of inaction, and the need for antibiotic stewardship. Antibiotic stewardship combined with infection prevention comprises a collaborative, multidisciplinary approach to optimise use of antibiotics. Efforts to mitigate overuse will be unsustainable without learning and coordinating activities globally.
Anti-infective drugs have had a key role in the contemporary world, contributing to dramatically decrease mortality rates caused by infectious diseases worldwide. Antimicrobial peptides (AMPs) are multifunctional effectors of the innate immune system of mucosal surfaces and present antimicrobial activity against a range of pathogenic viruses, bacteria, and fungi. However, the discovery and development of new antibacterial drugs is a crucial step to overcome the great challenge posed by the emergence of antibiotic resistance.
Natural World Heritage Sites (NWHS), via their formal designation through the United Nations, are globally recognized as containing some of the Earth's most valuable natural assets. Understanding changes in their ecological condition is essential for their ongoing preservation. Here we use two newly available globally consistent data sets that assess changes in human pressure (Human Footprint) and forest loss (Global Forest Watch) over time across the global network of terrestrial NWHS.
Trees, and their derivative products, have been used by societies around the world for thousands of years. Contemporary construction of tall buildings from timber, in whole or in part, suggests a growing interest in the potential for building with wood at a scale not previously attainable. As wood is the only significant building material that is grown, we have a natural inclination that building in wood is good for the environment. But under what conditions is this really the case?
This book chapter addresses goals 3, 12, and 15 by exploring the ability of African medicinal spices and vegetables to tackle malignant diseases.