Journal of Allergy and Clinical Immunology, Volume 149, June 2022

Mast cells are activated by IgE autoantibodies to autoallergens (type I autoallergy) or IgG-anti-IgE/IgG-anti-FcεRI autoantibodies (type IIb autoimmunity).
Chronic spontaneous urticaria (CSU) is a debilitating mast cell-driven disease characterized by recurrent wheals and/or angioedema. Type IIb autoimmune CSU is mediated by autoantibodies that activate mast cells and is present in less than 10% of patients with CSU
The paper supports SDG3, 11 and 15 by discussing the air pollution and the study will assist urban planners, policymakers, and health sectors.
This Series paper supports SDG 3 and 11 by presenting an expanded framework of pathways through which city planning affects health, incorporating 11 integrated urban system policies and 11 integrated urban and transport interventions addressing current and emerging issues.
This Series paper supports SDG 3 and 11 by identifying the minimum thresholds for urban design and transport features associated with two physical activity criteria: at least 80% probability of engaging in any walking for transport and WHO's target of at least 15% relative reduction in insufficient physical activity through walking.
This Series paper supports SDG 3 and 11 by assessing policy frameworks for city planning for 25 cities across 19 countries to identify whether these policies support the creation of healthy and sustainable cities.
The authors of this paper found limited impacts of a 3 year nutrition BCC (Behavior Change Communication) intervention through agriculture-focused SHGs (Self-Help Groups) on nutrition outcomes and on intermediate pathway indicators expected to lead to those outcomes. Despite these limited impacts, much can be learned from the studied effort to improve women’s nutrition through SHGs.
The immune disorders triggering the etiological mechanisms of depression are complex, and their biological effects involve multiple systems. Advances in clinical research provided new clues to the immunological mechanisms underlying the onset of depression, and continuous basic research provided a theoretical basis.
Background: Childhood traumatic events are risk factors for psychopathology, but large-scale studies of how childhood traumatic events relate to mental health and cognition in adulthood, and how the b
Background: Over 85% of Kibera's population, an informal settlement in Nairobi, Kenya, is food insecure.
This Commission supports SDG 3 by calling on all countries to both invest more and invest better in primary health care by designing their health financing arrangements in ways that place people at the centre and by addressing inequities first.