Health and population

Health and population dynamics are intertwined, embodying an intricate relationship with significant implications on the Sustainable Development Goals (SDGs). Health is fundamentally at the center of these 17 global goals, aimed to transform the world by 2030. Specifically, Goal 3 endeavors to "Ensure healthy lives and promote well-being for all at all ages." It acknowledges that health is pivotal to human life quality, social cohesion, and sustainable development. Inextricably linked to this are the complexities of population dynamics, including growth rates, age structure, fertility and mortality rates, and migration patterns.

With the world's population projected to exceed 9.7 billion by 2050, the pressure on health systems will undoubtedly escalate. The demographic transition, with an aging population and an increasing prevalence of non-communicable diseases, poses new challenges for health systems globally. Additionally, areas with high fertility rates often overlap with extreme poverty, resulting in heightened health risks, including higher maternal and child mortality rates, malnutrition, and infectious diseases.

Moreover, rapid urbanization and migration present both opportunities and threats to health. While urban areas may provide better access to healthcare, they also harbor risks of disease transmission, air and water pollution, and social determinants of health like inadequate housing and social inequality. Simultaneously, migrants often face disproportionate health risks due to unstable living conditions, exploitation, and limited access to healthcare services.

Achieving the SDGs will necessitate comprehensive approaches that consider the intricate interplay of health and population dynamics. It means strengthening health systems, promoting universal health coverage, and addressing social determinants of health. It also implies crafting policies that recognize demographic realities and foster an environment conducive to sustainable development. Only by understanding and harnessing these dynamics can the world meaningfully progress towards realizing the SDGs, ensuring healthy lives and well-being for all.

Elsevier,

Treatment of Skin Disease (Fifth Edition)
Comprehensive Therapeutic Strategies
2018, Pages 764-768

This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by providing information on scleroderma, a rare multisystem disease characterized by skin fibrosis, autoantibody production, and vascular abnormalities often leading to visceral disease.
Change in incidence rate over time in the Alzheimer's disease cohort for health conditions significantly associated with the disease.
An article on Alzheimer's disease risk, in the context of SDG 3, focusing specifically on the association between health conditions diagnosed in primary care and incident Alzheimer's disease.
An article on comorbid dementia and depression, in the context of SDG 3, focusing specifically on the effectiveness of music interventions on depressive symptoms for people with dementia.
An article on air pollution and cognitive decline, in the context of SDGs 3 and 11, focusing specifically on the association between exposure to outdoor air pollutants and cognitive performance.
Background: In response to a national call for re-evaluation of the use of race in clinical algorithms, the National Kidney Foundation (NKF) and the American Society of Nephrology (ASN) established a Task Force to reassess inclusion of race in the estimation of glomerular filtration rate (GFR) in the United States and its implications for diagnosis and management of patients with, or at risk for, kidney diseases.
Background: With much of the world's population residing in urban areas, an understanding of air pollution exposures at the city level can inform mitigation approaches. Previous studies of global urban air pollution have not considered trends in air pollutant concentrations nor corresponding attributable mortality burdens. We aimed to estimate trends in fine particulate matter (PM2·5) concentrations and associated mortality for cities globally.
Background: Road-traffic injuries are a key cause of death and disability in low-income and middle-income countries, but the effect of city characteristics on road-traffic mortality is unknown in these countries. The aim of this study was to determine associations between city-level built environment factors and road-traffic mortality in large Latin American cities. Methods: We selected cities from Argentina, Brazil, Chile, Colombia, Costa Rica, El Salvador, Guatemala, Mexico, Panama, and Peru; cities included in the analysis had a population of at least 100 000 people.
Elsevier,

Studies in Natural Products Chemistry, Volume 72, 2022, Pages 259-285

This chapter aligns with the SDG goal 3 of good health and wellbeing by summarizing hepatic diseases and inflammation and strategies to treat them.
Diabetic neuropathy is the most debilitating complication that can cause significant morbidity and mortality in type 1 and type 2 diabetic patients. It is essential to detect symptoms or signs of diabetic neuropathy and determine risk factors as early as possible to implement interventions and to prevent further neuronal damage. The goal of SDG 3.4 is to reduce by one third premature mortality from non-communicable diseases through prevention and treatment and promote mental health and well-being 3.4.1 Mortality rate attributed to cardiovascular disease, cancer, diabetes or chronic respiratory disease
Elsevier,

Blood, Volume 139, 17 February 2022

To date, most cancer clinical trials exclude all HIV-infected patients. The HIV Working Group has defined important principles related to eligibility criteria for HIV-infected patients with cancer. Notably, patients with CD4 count $350/mL should generally be eligible for any study, whereas lower CD4 count may be appropriate in the setting of second-line and later cancer therapy, assuming cART is carefully managed. All these studies will require multidisciplinary efforts.

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