Elsevier,
Brain Research, Volume 1841, 15 October 2024
This study found that female 5XFAD mice exhibit early impairments in prefrontal-dependent cognitive functions and increased activity of prefrontal PV neurons, unlike their male counterparts. These findings suggest a potential mechanism for the higher risk of Alzheimer's disease in women, highlighting sex-specific early deregulation in the prefrontal cortex.
Elsevier,
Pharmacological Research, Volume 208, October 2024
The study explores the use of a novel gene delivery system, AAV-aMTD-Parkin, to enhance motor and cognitive functions in animal models of Parkinson’s and Alzheimer’s diseases. This system improves the delivery efficiency of therapeutic proteins, potentially offering a new treatment approach for these neurodegenerative disorders.
Elsevier,
Applied Materials Today, Volume 40, October 2024
This text ties into SDG 6 (Clean Water and Sanitation) and SDG 12 (Responsible Consumption and Production). It focuses on the use of metal-organic frameworks (MOFs) for wastewater treatment, highlighting their potential to transform wastewater into a valuable resource and address water pollution challenges through innovative and sustainable methods.
Elsevier,
The Lancet Regional Health - Americas, Volume 37, September 2024
This paper supports SDG 3 with evidence of disparate effects of phased COVID-19 vaccine rollout on mental health across US populations, underlining the need for careful planning in future strategies for phased disease prevention and interventions.
Elsevier,
Brain Research, Volume 1838, 1 September 2024
The study demonstrates that the peptide PHDP5, which inhibits dynamin-MT interaction, can rescue impaired endocytosis and synaptic transmission caused by tau in presynaptic terminals. When administered intranasally to Alzheimer's disease (AD) model mice, PHDP5 significantly improved learning and memory, suggesting its potential as a candidate for human AD therapy.
