Elsevier, Annals of Hepatology, Volume 28, 1 March 2023
Introduction and Objectives: In clinical trials, patients with hepatitis C virus (HCV) genotype (GT)1a infection and baseline resistance-associated substitutions (RASs) at amino acid positions 28, 30, 31, or 93 receiving elbasvir/grazoprevir for 12 weeks achieved lower rates of sustained virologic response (SVR) than those without baseline RASs. SVR rates in patients with RASs were improved when elbasvir/grazoprevir treatment duration was extended from 12 to 16 weeks and administered concomitantly with ribavirin.
Elsevier,
Desalination, Volume 522, 15 January 2022
Results of ultrafiltration (UF) and reverse osmosis (RO) pilot plant on-site tests for wastewater reclamation are reported here with 90% and 65% water recovery achieved for UF and RO stages, respectively. RO achieved high quality requirements for industrial reuse supporting SDG 6.
Elsevier,
Preventive Medicine Reports, Volume 20, 2020, 101209, ISSN 2211-3355
Over 43 million U.S. residents rely on private unregulated wells for their drinking water, raising public health concerns, particularly in regions like northern New England where widespread groundwater arsenic contamination is now recognized. Children are particularly vulnerable to adverse health effects from arsenic exposure.
Earth Day is celebrated every year on April 22nd, and it is a global event aimed at raising awareness and promoting action towards environmental protection. It was first celebrated in 1970, and since then, it has become one of the largest civic events in the world, with over one billion people participating in activities such as clean-up campaigns, tree-planting initiatives, and educational programs. The theme for 2023 is Invest in Our Planet, a campaign that will focus on engaging governments, institutions, businesses and individuals in the fight against the climate crisis.
Elsevier,
Heliyon, Volume 9, March 2023
This paper investigates mitochondrial dysfunctions at an early event in the progression of neuropathological processes. It found that that mtDNA mutation is a major contributor to the metabolic pathology of most neurological disorders, causing changes in genes important for physiological homeostasis.
eClinicalMedicine, Volume 57, March 2023
In this systematic review the meausres to monitor and improve mental health outcomes in particpants taking part in SRHR/HIV interventions were assessed in sub-Saharan Africa. The authors show that interventions to improve adolescent SRHR, HIV, and mental health are relatively understudied, with mental health outcomes often the least commonly assessed outcomes. this study highlights the need to look beyond HIV care and keep in mind other equally important aspects of health and wellbeing.
Elsevier,
eClinicalMedicine, Volume 57, March 2023
In this 12 month long prospective cohort study, weight change in Black people in Johannesburg, South Africa, with HIV who switched from efavirenz to dolutegravir was compared with propensity score matched people who remained on efavirenz. Those who switched ART regimen where reported to have an increase in weight and 14.2 percentage point increase in the risk of hypertension. The study seeks to optimise the treatment regimens for people with HIV and hightlights the potnetially adverse effects of regimen switching.
The Organization for Women in Science for the Developing World and the Elsevier Foundation celebrated the 2023 OWSD-EF Awards for Women Scientists, with researchers from Benin, Bolivia, Guatemala, Palestine, Mongolia, South Africa and Sri Lanka. Awarding women scientists means not only recognizing their impressive work but empowering them to be role models. Read more about these incredible women! This article relates to SDG 5, Gender Equality.
