Elsevier,
Current Developments in Nutrition, Volume 7, November 2023
This paper concludes that it is imperative to identify effective, early treatments for Alzheimer's disease. Creatine is an important bioenergetic molecule, and the Creatine system is shown to be dysfunctional in the brain of individuals with Alzheimer's disease. Therefore, Ceatine may serve as a potential target for prevention and therapy and creatine monohydrate supplementation may be beneficial in Alzheimer's disease. To date, only rodent studies have investigated the use of creatine monohydrate as a treatment for Alzheimer's disease.. Thus, clinical trials investigating the effects of creatine monohydrateon cognition and creatine monohydrate’s mechanisms in humans with Alzheimer's disease as well as its potential as a strategy to prevent cognitive decline in those with normal cognition, are needed. There is much to be learned about CrM intervention and brain health in different life and disease phases.
Elsevier,
Translational Research in Anatomy, Volume 33, November 2023
The “contour smoothing” fractal analysis method can effectively examine cerebral hemispheres to detect and quantify age-related atrophic changes associated with normal or pathological aging. This method holds promise for clinical application in diagnosing neurodegenerative disorders, such as Alzheimer’s disease.
Elsevier,
Experimental Gerontology, Volume 183, November 2023
This study finds that pine nut peptide-zinc chelate improves Alzheimer's Disease (AD) in various ways which include (1) improving learning, memory, brain health, and gut balance in mice, and (2) treating cholinergic system changes, boosting cerebral antioxidants, and altering gut microbiota. Pine nut peptide-zinc chelate holds potential for AD therapy, requiring deeper mechanistic investigation.
Elsevier,
The Lancet Regional Health - Europe, Volume 34, November 2023
This Series paper supports SDG 3 by evaluating existing and emerging vaccines and vaccination campaigns against hepatitis B virus and other sexually transmitted infections, as well as other interventions such as PrEP for HIV
Elsevier,
eClinicalMedicine, Volume 65, November 2023
Previous studies have shown that people with HIV are at an increased risk of non-communicable diseases, this systematic review and meta-analysis collates data from 188 studies done in 21 sub-Saharan Africa countries and shows that people with HIV have an increased incidence of multiple NCDs, including hypertension, diabetes, and cervical cancer. Although more research is needed, this results highlight the need for improved treatment and prentative approaches to minimise the risk of people with HIV also developing non-comminicable diseases. Good health and wellbeing should not solely be focused on HIV managment; this study shows the growing risk of other diseases that have to be mitigated.
