The present numerical study investigated the transportation time of the inhaled chemicals in three realistic human airway models by adopting a methodology from the field of the building ventilation.
Elsevier,
Recent Advancements in Microbial Diversity, Macrophages and Their Role in Inflammation, 2022, Pages 361-395
This chapter aligns with the SDG goal 3 of good health and wellbeing by showing the current knowledge on the origins and composition of KCs, their functions in maintaining hepatic homeostasis, and their involvement in both promoting and resolving liver inflammation, injury, and fibrosis.
This article supports SDGs 3 and 10 by assessing racial and ethnic disparities in seasonal influenza vaccine uptake among older US adults. The findings show substantial disparities in uptake and suggest that new strategies are urgently needed to address these inequities.
This Article supports SDGs 3 and 10 by evaluating ethnic inequalities in health among older adults (55 years or older) in England. The large, cross-sectional study includes more than a million survey respondents, and identifies wide ethnic inequalities in health-related quality of life, prevalence of long-term conditions, experiences of primary care, support from local services, and confidence in managing one's own health. Outcomes varied widely between minority ethnic groups, both in the direction and magnitude of associations.
A hydro-economic assessment of the headwaters of the Nile River revealed the upstream-downstream linkages and interconnections among socio-economic development, climate change, and the environment.
This Viewpoint supports SDGs 3, 6, and 7 by discussing some of the reasons why many of the innovations and technologies for WASH (water, sanitation, and hygiene) and household air pollution developed in recent decades have not led to the expected improvements in health outcomes, and why many of these interventions have either been inconsistently adopted by low-income households, or not adopted at all.
Elsevier,
Understanding Female Offenders, Psychopathy, Criminal Behavior, Assessment, and Treatment, 2021, Pages 33-112
This chapter advances goals 3 and 5 by examining the range of common misconceptions and misinformation that permeates the female offender literature. Finally, we conclude with ten myths about female offenders and offer guidelines for identifying bias and how to avoid it.
Climate change can have detrimental effects on child health and wellbeing.
A Research Paper on food insecurity in the UK, in the context of SDGs 1, 2, and 3, focusing specifically on the association between the implementation of austerity policies in 2010 and the increase in foodbank use and food insecurity over the following decade.
Tauopathies are neurological disorders characterized by intracellular tau deposits forming neurofibrillary tangles, neuropil threads, or other disease-specific aggregates composed of the protein tau. Tauopathy disorders include frontotemporal lobar degeneration, corticobasal degeneration, Pick’s disease, and the largest cause of dementia, Alzheimer’s disease. The lack of disease-modifying therapeutic strategies to address tauopathies remains a critical unmet need in dementia care. Thus, novel broad-spectrum tau-targeted therapeutics could have a profound impact in multiple tauopathy disorders, including Alzheimer’s disease. Here we have designed a drug discovery paradigm to identify inhibitors of the pathological tau-enabling protein, MSUT2. We previously showed that activity of the RNA-binding protein MSUT2 drives tauopathy, including tau-mediated neurodegeneration and cognitive dysfunction, in mouse models. Thus, we hypothesized that MSUT2 inhibitors could be therapeutic for tauopathy disorders.
