Health and wellbeing

Health and well-being have a central role in the 17 Sustainable Development Goals (SDGs) endorsed by the United Nations, emphasizing the integral part they play in building a sustainable future. The third SDG explicitly calls for ensuring healthy lives and promoting well-being for all at all ages. This goal encompasses a wide range of health objectives, from reducing maternal and child mortality rates, combatting disease epidemics, to improving mental health and well-being. But beyond SDG 3, health is intrinsically linked with almost all the other goals.

When addressing SDG 1, which aims to end poverty, one cannot neglect the social determinants of health. Economic hardship often translates into poor nutrition, inadequate housing, and limited access to health care, leading to a vicious cycle of poverty and poor health. Similarly, achieving SDG 2, ending hunger, also contributes to better health through adequate nutrition, essential for physical and mental development and the prevention of various diseases.

Conversely, the repercussions of climate change, encapsulated in SDG 13, profoundly impact health. Rising global temperatures can lead to increased spread of infectious diseases, compromised food and water supplies, and increased frequency and intensity of extreme weather events, all posing severe health risks. Conversely, the promotion of good health can also mitigate climate change through the reduction of carbon-intensive lifestyles and adoption of healthier, more sustainable behaviors.

SDG 5, advocating for gender equality, also has substantial health implications. Ensuring women's access to sexual and reproductive health services not only improves their health outcomes, but also contributes to societal and economic development. Furthermore, achieving SDG 4, quality education, is also critical for health promotion. Education fosters health literacy, empowering individuals to make informed health decisions, hence improving overall community health.

Lastly, SDG 17 underlines the importance of partnerships for achieving these goals. Multi-sector collaboration is vital to integrate health considerations into all policies and practices. Stakeholders from various sectors, including health, education, agriculture, finance, and urban planning, need to align their efforts in creating sustainable environments that foster health and well-being.

Hence, the relationship between health, well-being, and the SDGs is reciprocal. Improving health and well-being helps in achieving sustainable development, and vice versa. In this context, health and well-being are not just outcomes but are also powerful enablers of sustainable development. For the world to truly thrive, it must recognize and act upon these interconnections.

This content aligns with Goal 3: Good Health and Goal 13: Climate Action by exploring the relationship between mental health and climate anxiety in subjects of differing ages.
This content aligns with Goal 3: Good Health by highlighting the significant impact of climate change on mental health, emphasizing the need for awareness and interventions to address both physical and psychological health issues caused by environmental changes. By identifying the mental health risks associated with climate change and advocating for further research and interventions, the study aims to improve overall well-being and resilience among affected individuals. Additionally, it supports Goal 10: Reduced Inequalities by underscoring the universal nature of these mental health challenges, showing that climate change affects diverse populations regardless of age or gender, and advocating for equitable access to mental health support and resources to mitigate these risks for all individuals.

The article presents the development of a novel fusion delivery platform called AAV-aMTD-Parkin, which combines a hydrophobic cell-penetrating peptide sequence with the DNA sequences of AAV and Parkin. This innovative approach has demonstrated significant improvements in cell and tissue permeability, leading to the restoration of motor and cognitive function in animal models of Parkinson's disease (PD) and Alzheimer's disease (AD).

This Article supports SDG 3 by presenting strong evidence of negative effects of ear disease and/or hearing loss on all measured cognitive domains in a cohort of children enrolled in a randomized placebo-controlled trial of an 11-valent pneumococcal conjugate vaccine conducted between 2000 and 2004 in Bohol, Philippines.
This Article supports SDG 3 by demonstrating the cost-effectiveness of a multi-center multidisciplinary co-managed care model for hip fracture patients in China.
This paper supports SDG 3 and 8 by examining firearm and non-firearm related suicide in current and former US service members.

This paper analyzes Danish population data to identify and compare three distinct transgender subpopulations: those who changed their legal sex, those with trans-related medical diagnoses, and those who self-identify as transgender in surveys, revealing significant differences in socioeconomic and health outcomes among them. It highlights that transgender individuals seeking medical or legal transition face greater disadvantages, and that survey-based estimates do not fully capture the diversity or needs of the transgender population.

Dementia is a global leading cause of disability and death among older adults, and there is a need to carefully evaluate existing evidence on related risk factors to guide future research. This review summarized and evaluated the most updated evidence on associations of various magnesium forms (supplements, dietary intake, and biomarkers) with cognitive outcomes in adults, based on evidence from randomized controlled trials and cohort studies.
This study focuses on neuroimaging methods such as structural magnetic resonance imaging (sMRI) and fluorodeoxyglucose positron emission tomography (FDG-PET) have been used to diagnose and categorize AD
This review discusses the impact of Apolipoprotein-E4 (ApoE4) on cognitive performance in targeted-replacement human ApoE knock-in mice, finding that ApoE4 mice exhibit significant cognitive deficits compared to ApoE3 mice in various cognitive tests, indicating an intrinsic vulnerability in ApoE4 mice that may be exacerbated in the context of neurodegenerative diseases.

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